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Report of two cases of ciliary body mesectodermal leiomyoma: unique expression of neural markers.

Odashiro, Alexandre N; Fernandes, Bruno F; Al-Kandari, Abdullah; Gregoire, Francois J; Burnier, Miguel N.

Ophthalmology ; 114(1): 157-61, 2007 Jan.

Article in English | MEDLINE | ID: mdl-17070579

ABSTRACT

OBJECTIVE: Mesectodermal leiomyoma of the ciliary body is a rare tumor with, to our knowledge, only 15 cases reported in the literature. It has a neural histopathologic appearance and a presumed origin from neural crest. DESIGN: Case report. RESULTS: Two cases of mesectodermal leiomyoma with histopathologic and immunohistochemical confirmation are reported. CONCLUSIONS: For the second time, we were able to demonstrate expression of neural immunohistochemical markers in this tumor.

Subject(s)

Biomarkers, Tumor/metabolism , Ciliary Body/metabolism , Leiomyoma/metabolism , Nerve Tissue Proteins/metabolism , Uveal Neoplasms/metabolism , Actins/metabolism , Adult , Antigens, Neoplasm , Ciliary Body/pathology , Female , Glial Fibrillary Acidic Protein/metabolism , Humans , Immunohistochemistry , Keratins/metabolism , Leiomyoma/pathology , Male , Melanoma-Specific Antigens , Middle Aged , Muscle Proteins/metabolism , Neoplasm Proteins/metabolism , Uveal Neoplasms/pathology , Vimentin/metabolism

ABSTRACT

Subject(s)

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