Prostaglandin infusion therapy for intermittent digital ischemia in a patient with mixed connective tissue disease. Case report and review of the literature.

Intermittent digital ischemia is frequently resistant to therapy despite various treatment modalities. Recent studies have reported the successful treatment of intermittent digital ischemia with prostaglandin infusion therapy. We present a severe case of intermittent digital ischemia associated with mixed connective tissue disease, responsive to prostaglandin E1 infusion therapy.