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Probl Radiac Med Radiobiol ; 23: 481-489, 2018 Dec.
Article in English, Ukrainian | MEDLINE | ID: mdl-30582865

ABSTRACT

OBJECTIVE: evaluate the retinal morphometric parameters of the reconvalescents in remote period after acute radi-ation sickness. MATERIALS AND METHODS: A complete ophthalmologic examination was carried out on 7 reconvalescents of acuteradiation sickness. The examined are divided into two subgroups: 1) patients with macular degeneration of the reti-na (8 eyes); 2) patients without clinical signs of macular pathology (6 eyes). Parameters of the retina in the cen-tral retina zone studied using the method of optical coherence tomography. To evaluate the results of surveys usedstatistical methods: average values of quantitative indicators calculation, estimation of probability difference byStudent's method. RESULTS: Optical coherence tomography revealed a statistically significant increase of the thickness of the retina inthe fovea in all reconvalescents of acute radiation sickness. CONCLUSIONS: It was shown that the thickness of the retina in the fovea and paramacular zone in persons who suf-fered acute radiation sickness is significantly higher than in the control. These changes observed in all reconvalis-cents ARS - both in person with sings of macular degeneration, and in those whose clinical manifestations were notdetected. The presence of a correlation between the volume of the retina in the macular zone and the documentedradiation dose of the study group emphasizes the perspectives of next OCT examination of the retina of reconvales-cents of ARS to study the mechanism of retina's damage in this category of victims of the Chornobyl accident.


Subject(s)
Chernobyl Nuclear Accident , Environmental Exposure/adverse effects , Fovea Centralis/pathology , Macular Degeneration/pathology , Radiation Exposure/adverse effects , Radiation Injuries/pathology , Acute Disease , Aged , Aged, 80 and over , Convalescence , Environmental Exposure/analysis , Female , Fovea Centralis/diagnostic imaging , Humans , Longitudinal Studies , Macular Degeneration/diagnostic imaging , Macular Degeneration/etiology , Male , Middle Aged , Radiation Dosage , Radiation Exposure/analysis , Radiation Injuries/diagnostic imaging , Radiation Injuries/etiology , Radiation, Ionizing , Tomography, Optical Coherence , Ukraine
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