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AIDS ; 26(4): 523-6, 2012 Feb 20.
Article in English | MEDLINE | ID: mdl-22210631

ABSTRACT

HIV-infected patients may develop rare anogenital pseudotumoral herpes potentially mimicking epidermoid carcinoma. We assessed treatment in five new cases with a median follow-up of 3.3 years. Recurrence and clinical nucleoside analog resistance were observed in all patients. All drug treatments were only temporarily curative and clinical responses varied between patients and recurrences. Foscavir seemed to be the most appropriate second-line treatment and cidofovir or thalidomide should be considered as alternative treatments.


Subject(s)
AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Antiviral Agents/therapeutic use , Condylomata Acuminata/diagnosis , Condylomata Acuminata/virology , Papillomavirus Infections/diagnosis , Papillomavirus Infections/drug therapy , Adult , Carcinoma, Squamous Cell/diagnosis , Cidofovir , Cytosine/analogs & derivatives , Cytosine/therapeutic use , Diagnosis, Differential , Female , Foscarnet/therapeutic use , Humans , Male , Middle Aged , Organophosphonates/therapeutic use , Thalidomide/therapeutic use , Treatment Outcome , Tumor Virus Infections/diagnosis , Tumor Virus Infections/drug therapy
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