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1.
Klin Khir (1962) ; (3): 25-7, 1989.
Article in Russian | MEDLINE | ID: mdl-2733357

ABSTRACT

The applicative-sorptive method of treatment was used by the authors in 57 patients ranging in age from 18 to 60 years with II-III AB degree burns of 10 to 50% of the body surface. The decrease in activity of proteolytic enzymes in the wound discharge, the increase in the activity of microbicidal systems of neutrophilic leukocytes, and formation of a phagocytic type of local resistance of an organism were noted. The epithelization of II-III A degree burn wounds accelerated, and the area of deep burn wounds reduced in patients.


Subject(s)
Burns/therapy , Dimethylpolysiloxanes/therapeutic use , Silicones/therapeutic use , Adolescent , Adsorption , Adult , Humans , Middle Aged
6.
Vopr Pitan ; (6): 30-5, 1980.
Article in Russian | MEDLINE | ID: mdl-6162275

ABSTRACT

It has been extablished that in the course of protein starvation in dogs, parenteral administration of amikin or aminozol normalizes, to a greater of less extent, the disturbed metabolism of proteins, nucleoproteins, glycogen and lipids. Electron microscopy has shown that the ingredients of the preparations enter the cells at an equal intensity from the microcirculatory bed by means of active transendothelial transport. In the course of utilization of the substances supplied to the cells, no marked changes were seen in protein synthesis or in its participation in intracellular reparative regeneration. There occurs a pronounced cytosegresomal response to unutilized substances accumulated by hepatocytes. The clinical efficacy of the preparations used is related to the processes of gluconeognesis of amino acids supplied as a result of which energy formation does not require structural or endogenously formed protein.


Subject(s)
Amino Acids/metabolism , Microscopy, Electron , Nitrogen/metabolism , Parenteral Nutrition , Protein Hydrolysates/metabolism , Animals , Biological Transport, Active , DNA/metabolism , Dogs , Drug Evaluation, Preclinical , Liver/pathology , Protein Deficiency/metabolism , Protein Deficiency/pathology , Protein Deficiency/therapy , RNA/metabolism
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