ABSTRACT
Pancreatitis was previously an unknown disease among black South Africans but has recently emerged as a common clinical problem. This has taken place pari passu with a change in the pattern of alcoholic consumption--Western-type spirits in addition to home-brews. Seventy patients with chronic alcoholic pancreatitis manifesting as clinically acute pancreatitis, and 90 patients with chronic calcific pancreatitis were studied. A high alcohol intake was associated with the pancreatitis in all cases. The prognosis in clinically acute pancreatitis was good, whereas chronic calcific pancreatitis has a high morbidity and mortality rate.
Subject(s)
Alcoholism/complications , Pancreatitis/etiology , Acute Disease , Adult , Black or African American , Aged , Black People , Chronic Disease , Female , Humans , Male , Middle Aged , South AfricaABSTRACT
The clinical manifestations of sporotrichosis can be classified into three disease patterns: (1) localized lymphatic sporotrichosis, (2) fixed cutaneous (or endemic) sporotrichosis, and (3) disseminated sporotrichosis. This presentation reflects a rare disseminated form of the disease with extensive cutaneous and systemic lesions, and further illustrates the difficulty in diagnosing systemic sporotrichosis infection.
Subject(s)
Sporotrichosis/pathology , Dermatomycoses/complications , Dermatomycoses/diagnosis , Dermatomycoses/pathology , Female , Humans , Middle Aged , Skin/pathology , Sporotrichosis/complications , Sporotrichosis/diagnosis , Tuberculosis, Pulmonary/complicationsABSTRACT
A 5-year-old boy with acute myeloblastic leukaemia had large-bowel masses, demonstrated at autopsy, 5 weeks after an episode of Streptococcus bovis bacteraemia. The association of Strept. bovis bacteraemia with large-bowel disease, well documented in adults, should be considered in children.
Subject(s)
Cecal Diseases/complications , Colonic Diseases/complications , Leukemia, Myeloid, Acute/complications , Sepsis/complications , Streptococcal Infections/complications , Child, Preschool , Humans , MaleABSTRACT
Primary lymphoma of the small bowel resulting in pancreatic duct or biliary obstruction is rare. Only 1 case of pancreatic obstruction causing pancreatitis has previously been reported. A patient with primary small-bowel lymphoma of the 'Western' variety is described. This was associated with extensive duodenal involvement and obstruction of the pancreatic and biliary system accompanied by obstructive jaundice and pancreatitis.
Subject(s)
Cholestasis, Extrahepatic/etiology , Duodenal Neoplasms/complications , Lymphoma/complications , Pancreatitis/etiology , Constriction, Pathologic/etiology , Humans , Male , Middle Aged , Pancreatic Ducts/pathologyABSTRACT
A rare verrucous form of Bowen's disease in a black subject is presented. Bowen's disease is extremely rare in blacks, but when it does occur, it tends to present in an atypical fashion.
Subject(s)
Bowen's Disease/pathology , Carcinoma, Squamous Cell/pathology , Skin Neoplasms/pathology , Warts/pathology , Aged , Black People , Bowen's Disease/complications , Humans , Male , Skin/pathology , Skin Neoplasms/complications , South Africa , Warts/complicationsABSTRACT
Atypical Kyrle's disease developed on the limbs and on the palmar and plantar surfaces of an African man. Unusual histopathologic features, such as degenerating cells under the parakeratotic plug and eccrine duct in the parakeratotic plug, are described and the diagnostic criteria for Kyrle's disease are reviewed.
Subject(s)
Keratosis/pathology , Adult , Etretinate/administration & dosage , Etretinate/therapeutic use , Humans , Keratosis/drug therapy , Male , Skin/pathology , Syndrome , Time FactorsABSTRACT
A case of sebaceous cell carcinoma of the parotid gland in a black woman is described. The pathology, treatment and prognosis of this rare tumour are discussed.
Subject(s)
Adenocarcinoma/pathology , Parotid Neoplasms/pathology , Sebaceous Gland Neoplasms/pathology , Adenocarcinoma/surgery , Aged , Female , Humans , Parotid Neoplasms/surgery , Sebaceous Gland Neoplasms/surgeryABSTRACT
We encountered a case of elastosis perforans serpiginosa in a patient with coexisting renal disease, the first such reported association of which we are aware. The perforating disorders tend to have atypical clinical features when associated with renal disease. The exact pathogenic mechanism by which renal disease predisposes to a perforating disease remains to be elucidated but is likely to be related to minor trauma, which occurs in renal disease.
