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1.
Ann Emerg Med ; 70(6): 825-834, 2017 Dec.
Article in English | MEDLINE | ID: mdl-28935285

ABSTRACT

STUDY OBJECTIVE: We determine whether omitting the pelvic examination in emergency department (ED) evaluation of vaginal bleeding or lower abdominal pain in ultrasonographically confirmed early intrauterine pregnancy is equivalent to performing the examination. METHODS: We conducted a prospective, open-label, randomized, equivalence trial in pregnant patients presenting to the ED from February 2011 to November 2015. Patients were randomized to no pelvic examination versus pelvic examination. Inclusion criteria were aged 18 years or older, English speaking, vaginal bleeding or lower abdominal pain, positive ß-human chorionic gonadotropin result, and less than 16-week intrauterine pregnancy by ultrasonography. Thirty-day record review and follow-up call assessed for composite morbidity endpoints (unscheduled return, subsequent admission, emergency procedure, transfusion, infection, and alternate source of symptoms). Wilcoxon rank sum tests were used to assess patient satisfaction and throughput times. RESULTS: Only 202 (of a planned 720) patients were enrolled, despite extension of the study enrollment period. The composite morbidity outcome was experienced at similar rates in the intervention (no pelvic examination) and control (pelvic examination) groups (19.6% versus 22.0%; difference -2.4%; 90% confidence interval [CI] -11.8% to 7.1%). Patients in the intervention group were less likely to report feeling uncomfortable or very uncomfortable during the visit (11.2% versus 23.7%; difference -12.5; 95% CI -23.0% to -2.0%). CONCLUSION: Although there was only a small difference between the percentage of patients experiencing the composite morbidity endpoint in the 2 study groups (2.4%), the resulting 90% CI was too wide to conclude equivalence. This may have been due to insufficient power. Patients assigned to the pelvic examination group reported feeling uncomfortable more frequently.


Subject(s)
Abdominal Pain/etiology , Emergency Service, Hospital , Gynecological Examination , Uterine Hemorrhage/etiology , Abdominal Pain/diagnosis , Abdominal Pain/diagnostic imaging , Adult , Female , Humans , Patient Satisfaction , Pregnancy , Ultrasonography , Uterine Hemorrhage/diagnosis , Uterine Hemorrhage/diagnostic imaging
2.
Emerg Med Clin North Am ; 34(3): 575-99, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27475016

ABSTRACT

Neurologic diseases are a major cause of death and disability in elderly patients. Due to the physiologic changes and increased comorbidities that occur as people age, neurologic diseases are more common in geriatric patients and a major cause of death and disability in this population. This article discusses the elderly patient presenting to the emergency department with acute ischemic stroke, transient ischemic attack, intracerebral hemorrhage, subarachnoid hemorrhage, chronic subdural hematoma, traumatic brain injury, seizures, and central nervous system infections. This article reviews the subtle presentations, difficult workups, and complicated treatment decisions as they pertain to our older patients."


Subject(s)
Nervous System Diseases/diagnosis , Age Factors , Aged , Brain Injuries, Traumatic/diagnosis , Brain Injuries, Traumatic/therapy , Brain Ischemia/diagnosis , Brain Ischemia/therapy , Central Nervous System Infections/diagnosis , Central Nervous System Infections/therapy , Cerebral Hemorrhage/diagnosis , Cerebral Hemorrhage/therapy , Emergencies , Emergency Service, Hospital , Hematoma, Subdural, Chronic/diagnosis , Hematoma, Subdural, Chronic/therapy , Humans , Ischemic Attack, Transient/diagnosis , Ischemic Attack, Transient/therapy , Nervous System Diseases/physiopathology , Nervous System Diseases/therapy , Seizures/diagnosis , Seizures/therapy , Subarachnoid Hemorrhage/diagnosis , Subarachnoid Hemorrhage/therapy
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