[General mechanism of ozone decomposition in physiologic solutions and a method for evaluation of the ozone dose in solutions administered to patients].

Ozone solutions in water and in NaCl solutions found are widely used in technology and medicine. Some times ozone employment meets difficulties due to instability of ozone in solution. The paper describes the results of study of ozone decomposition prepared using solutions in distilled water, solutions of NaCl in water, including physiologic solutions from different manufacturers. Also it was proposed the reaction mechanisms explained influence of OH- and Cl- ions on the decomposition rate. Experimental follow the monomolecular law and are described by a straight line in Ig(Ct/C0) = f(t) coordinates. It can be used as a basis for a new method of evaluation of real ozone dose introduced to patients.

[The experience with endolumbar application of cerebrolysin in hemispheric ischemic stroke]. / Opyt éndoliumbarnogo vvedeniia tserebrolizina pri polusharnom ishemicheskom insul'te.

The purpose of the investigation was to evaluate the efficiency of therapy of patients with hemispheric ischemic stroke with cerebrolysin (C) (using two different regimens of its injections) versus placebo. One endolumbar C injection (5 ml) made in the first 12 hours of stroke and after the subsequent therapy with dropwise C injections (10 ml) significantly enhanced the efficiency of therapy and improved the functional recovery of patients was observed 12 hours following.

[Osmolality and ion concentration in the cerebrospinal fluid and blood serum in epilepsy and ischemic stroke]. / Osmolial'nost' i kontsentratsiia ionov v likvore i syvorotke krovi pri épilepsii i ishemicheskom insul'te.

A sharp (16.4%) increase of blood serum osmolality very close to the critical values was found in acute period of ischemic stroke, while sodiumemia exceeded the normal levels by 50 mmol/l and more. Meanwhile, the concentrations of Na ions in liquor of such patients was not significantly increased. The levels of Ca, K, Mg ions as well as the osmolality of blood serum and liquor were stable too. The alterations of these parameters were not significantly changed in epileptic patients out of fits. Both the analysis of the reasons of hyperosmia and hypersodiumemia development and the search for the methods of their prophylaxis and correction will be quite important in further investigations.

[Incidence and the degree of compensation of diseases of the nervous system]. / O rasprostranennosti i stepeni kompensatsii zabolevanii nervnoi sistemy.

Based on the results of a clinicoepidemiological examination of the population of one of the medical districts of Leningrad and of the rural community (altogether 14,600 persons), marked differences were established in the general incidence of nervous system diseases (595.3% and 199.6%, respectively) as were 15 main patterns of neurological pathology. The incidence of nervous diseases was found to be fairly high, especially among women, which was supported by the data on 7 organized populations (overall 10.1 thousand persons). Factors of urbanization were shown to have an adverse effect on the population health status, manifesting, first of all, in a direct relationship between the incidence of initial signs of cerebral circulation failure and the number of the urban population. In the organized populations of the cities, the number of patients with the most unfavourable course of nervous system diseases (subcompensated and decompensated patterns) reached 21.5% of the total number of persons afflicted with chronic diseases of the nervous system. Meanwhile in the organized rural community, it was only 9.2%.