Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Org Lett ; 12(19): 4328-31, 2010 Oct 01.
Article in English | MEDLINE | ID: mdl-20795632

ABSTRACT

A convergent stereoselective synthesis of a C1/C14 bis-epimer of uprolide D is described in which an intramolecular Barbier-type reaction was employed for macrocyclization with concomitant introduction of the C1 and C14 stereocenters of a fused α-methylene lactone ring through an anti-Felkin-Anh transition state. Unlike previous examples of allyl chromium additions, none of the Felkin-Anh derived adduct could be detected.


Subject(s)
Bridged-Ring Compounds/chemical synthesis , Lactones/chemical synthesis , Organic Chemicals/chemical synthesis , Chelating Agents/chemistry , Molecular Structure , Stereoisomerism
SELECTION OF CITATIONS
SEARCH DETAIL
...