Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Publication year range
1.
Bull Exp Biol Med ; 143(1): 72-4, 2007 Jan.
Article in English | MEDLINE | ID: mdl-18019017

ABSTRACT

In human cells, expression of IL-4 gene involves alternative mRNA splicing. IL-4delta2 splice variant is an antagonist of full-length IL-4 protein and blocks its effect on the functional activity of immunocompetent cells. The effect of recombinant IL-4delta2 on cytokine-producing activity of human peripheral blood mononuclear cells is shown for the first time.


Subject(s)
Interleukin-4/pharmacology , Leukocytes, Mononuclear/drug effects , Alternative Splicing , Cell Proliferation/drug effects , Humans , Immunoglobulin E/biosynthesis , Immunoglobulin E/blood , In Vitro Techniques , Interleukin-4/genetics , Interleukin-6/biosynthesis , Interleukin-6/blood , Interleukin-6/genetics , Leukocytes, Mononuclear/cytology , Leukocytes, Mononuclear/metabolism , Recombinant Proteins/pharmacology
SELECTION OF CITATIONS
SEARCH DETAIL
...