[Use of genetic analysis methods in examining patients with endometrial cancer]. / Ispol'zovanie metodov geneticheskogo analiza pri obsledovanii bol'nykh rakom éndometriia.

An analysis of clinical and family history of 36 patients with endometrial cancer revealed clustering of tumors in some families. Cytogenetic studies of peripheral lymphocytes showed increased counts of aberrant cells in patients with endometrial cancer as against their values in normal women and patients with endometrial hyperplasia.

[Mitotic regime in human neoplasms of the stomach, corpus uteri, breast and skin]. / Issledovanie mitoticheskogo rezhima v novoobrazovaniiakh zheludka, tela matki, molochnoi zhelezy i kozhi cheloveka.

The mitotic regime in 362 human tumours of different genesis was studied by the same technique. The data obtained were compared with the histological structure of the tumours and the degree of thier anaplasia. Significance of the observed changes in the mitotic regime for the differential diagnostics of benign and malignant processes and for a complex estimation of biological characteristics of neoplasms is discussed.

[Comparative study of the karyotype and histostructure of neoplasms of the uterine body, stomach and malignant melanoma]. / Sravnitel'noe izuchenie kariotipa i gistostruktury novoobrazovanii tela matki, zheludka i zlokachestvennoi melanomy.

Direct analysis of karyotype revealed a heterogeneity of chromosome composition, variations in modal lines and chromosome aberrations, diversity of marker chromosome morphology. The variability of cytogenetic alterations was found in tumors both of the same and of different origin. These results established the nature of genome and chromosome alterations in the investigated tumors. The problem is discussed of a possible use of cytogenetic analysis for a more concrete characterization of human tumors in terms of their biological features.