ABSTRACT
The paper reports a rare case of intranasal meningoencephalocele in a 64-year-old female, simulating clinically a nasal polyp. A histological investigation of the removed polyp showed that it was composed mainly of malformed brain tissue with meninx vasculosa. The authors suggest a congenital nature of this formation.
Subject(s)
Encephalocele/pathology , Meningocele/pathology , Diagnosis, Differential , Encephalocele/surgery , Female , Humans , Meningocele/surgery , Middle Aged , Nasal Cavity , Nasal Polyps/pathology , Nasal Polyps/surgeryABSTRACT
A clinically unclear case is described of stomatitis with a long duration in a male of 28. Exfoliations in the region of the mouth angle were observed resembling pemphigus vegetans. Biopsy examination revealed a thick plasma cell infiltration which was considered to be an extramedullary plasmacytoma. However, a polyclonal composition of plasmacytes was found immunomorphologically producing immunoglobulins A, M and G with predominant production of IgG. This allowed rejection of neoplastic nature of the infiltrate, confirming its inflammatory origin and specific character. Serological tests (Wassermann, immunofluorescence test, in vitro immobilization test) confirmed the diagnosis of secondary recurring syphilis. Differential diagnosis of plasma-cell syphilid of skin and mucosal extramedullary plasmacytoma is under discussion.
Subject(s)
Mouth Neoplasms/pathology , Plasmacytoma/pathology , Syphilis/pathology , Adult , Diagnosis, Differential , Humans , Immunoglobulins/analysis , Male , Mouth Mucosa/immunology , Mouth Mucosa/pathology , Mouth Neoplasms/immunology , Plasma Cells/immunology , Plasma Cells/pathology , Plasmacytoma/immunology , Recurrence , Stomatitis/immunology , Stomatitis/pathology , Syphilis/immunology , Syphilis Serodiagnosis , Syphilis, Cutaneous/immunology , Syphilis, Cutaneous/pathologyABSTRACT
A 47-year-old man had ulcero-necrotic pharyngitis examined and treated without effect in various Moscow hospitals for 3 months. The diagnosis was established after histologic and bacteriologic examination of the biopsy.
Subject(s)
Pharyngitis/pathology , Tuberculosis, Laryngeal/pathology , Biopsy , Humans , Hypopharynx/pathology , Male , Middle Aged , Necrosis , Pharyngitis/microbiology , Tuberculosis, Laryngeal/diagnosisABSTRACT
As many as 100 children aged 3 months to 4 years with lymphaticohypoplastic diathesis (LHD) were examined for clinico-immunologic++ interrelations. The children suffering from manifest LHD demonstrated the reduction of the amount of circulating T lymphocytes and IgA, IgM and IgG subpopulations. At the same time the changes in local immunity correlating with enlargement of the thymus and lymphoid formations in the nasopharynx were identified. The immunity unbalance in LHD was supported by morphologic and immunologic studies of the tissue of the removed hypertrophied tonsils. The specification of the deranged mechanisms of immunity in LHD requires early diagnosis of the illness, screening of the methods for immunocorrection and closer follow-up of the sick children.
