[Application of physiological loadings in evaluation of intracranial volume-pressure relations. II. Clinical studies]. / Zastosowanie obciazen fizjologicznych w ocenie wewnatrzczaszkowych stosunków objetosciowo-cisnieniowych. II. Badania kliniczne.

The effects of physiological loadings (venous pressure increase, postural changes, pCO2 increase) on intracranial volume-pressure relations were studied. The standardized increase of venous outflow pressure was found to be a good test for the evaluation of CSF outflow routes. Standardized venous outflow pressure increase in Queckenstedt test seems to be especially useful.

[Evaluation of work capacity in cases of discopathy of the lumbosacral segment of the spine]. / Ocena przydatnosci zawodowej w przypadkach dyskopatii odcinka ledzwiowo-krzyzowego kregoslupa.

The ability to resume occupational work in cases of lumbar discopathy was assessed in an analysis of 1104 cases treated in a period of 25 years. The assessment was analysed in relation to the following factors: 1. disease duration, 2. discopathy type, 3. patient's age, 4. occupation type, 5. treatment. The paper contains a number of observations concerning the management of lumbar discopathy, and suggestions related to working ability expertise in such cases.

Intracranial volume reserve determination using CT images, numerical analysis and lumbar infusion tests. An experimental study.

The epidural balloon compression model in the cat was used in intracranial volume reserve studies. The evaluation of the intracranial volume-pressure relations was based on the lumbar infusion test data: intracranial pressure, CSF outflow resistance, volume-pressure response and on CT images numerical analysis (CTINA) values. Two methods were applied and compared in the study: lumbar infusion test and CT images numerical analysis. The determinations were performed at the balloon volumes of 0.5 ml, 1.0 ml, and 1.5 ml. First statistically significant changes were found at the balloon volume of 0.5 ml i.e. the increase of CSF outflow resistance and volume-pressure response (data obtained in lumbar infusion test) and the decrease in CTINA values. The rise of intracranial pressure was less informative as it was observed at the balloon volume of 1.5 ml. Therefore CTINA seems to be a very useful noninvasive screening method in clinical studies of intracranial volume reserve.

[Occlusion of the superior sagittal sinus caused by meningioma, intracranial volume-pressure relations and brain edema]. / Niedroznosc zatoki strzalkowej górnej spowodowana oponiakiem a wewnatrzczaszkowe stosunki objetosciowo-cisnieniowe i obrzek mózgu.

Fifty-one cases of parasagittal meningiomas were analysed. In 37 cases the tumour was situated in the middle and posterior part of the falx. In 17 cases occlusion of the superior sagittal sinus was diagnosed and confirmed by angiography. No correlation was found between the extent of brain oedema and sinus occlusion and tumour size. However, extensive oedema was present in tumours of high malignancy. Occlusion of the sagittal sinus caused no increase of intracranial pressure or venous stasis. This suggests that sinus occlusion caused by meningioma is completely compensated and has no effect on the preoperative and postoperative course.

CSF absorptive capacity in patients without intracranial pathology.

The role of changes in CSF inflow in patients without intracranial pathology has been studied. The CSF outflow resistance has been calculated, by dividing the CSF pressure rise by the speed of intrathecal saline infusion. The average CSF pressure rise produced during infusion test (infusion 2 ml/min) amounted to 11.15 mmHg. The calculated CSF outflow resistance equaled to 5.58 +/- 1.1 mm Hg/ml/min. On-line computer assisted analysis during infusion test helps to shorten the procedure and makes it more precise.

[Cerebrospinal fluid lactates following craniocerebral injuries]. / Mleczany w plynie mózgowo-rdzeniowym po urazach czaszkowo-mózgowych

CSF lactate concentration was determined in 37 patients after craniocerebral injury. In 26 cases the lactate concentration was raised above the normal value (15 mg/100 ml) and in 11 cases it was above 30 mg/100 ml. All fatal cases were in the group with lactate level above 30 mg/100 ml. The study confirms the fact that CSF lactate concentration is related to the severity of cerebral tissue damage and has a prognostic significance.

A method of estimating intracranial decompensation in man.

A new method of estimating intracranial decompensation in man is described. An on-line computer system is connected to an intracranial pressure (ICP) monitoring system to compute regression plots of mean ICP vs standard deviation; standard deviation is used as a measure of ICP instability. Two zones with distinctly different slopes are a characteristic feature of these plots. It is thought that the changes of slope signify intracranial decompensation.

[Chronic leukemia coexisting with hypophyseal tumor]. / Wspólistnienie przewleklej bialaczki z guzem przysadki mózgowej

The author describes a case of hypophyseal tumor coexisting with chronic leukaemia. It is suggested that both these processes coexisted from the very beginning of the disease. Development of hypothalmo-hypophyseal system failure was due to the presence of hypophyseal tumour while intensification of these manifestations in the last stage of the disease was caused by the presence of leukaemic changes in the central nervous system.

[Spread of pituitary adenomas beyond the sella]. / Szerzenie sie gruczolaków przysadki mózgowej poza siodlo tureckie

Two cases of giant pituitary adenomas spreading extensively beyound the sella are described. In the 1st case death occurred 18 hours after the operation, in the 2nd case a good result was obtained by operation from subtemporal approach followed by 60Co radiotherapy. Control scintigraphic and angiographic examinations 11 months after treatment failed to demonstrate the signs which indicated extrasellar spread of adenoma before treatment.