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1.
Transmission of human immunodeficiency virus type 1 nevirapine resistance mutation K103N from a treatment-naive mother to her child.
Schmitz, Thomas; Kleinkauf, Niels; Klempa, Boris; Ringe, Hannelore; Varnholt, Verena; Grosch-Wörner, Ilse.
Pediatr Infect Dis J ; 25(3): 275-6, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16511398

ABSTRACT

Vertical infection of drug-resistant human immunodeficiency virus type 1 (HIV-1) has occasionally been reported in children from pretreated mothers with HIV-1 infection. In this report, a treatment-naive mother transmitted HIV-1 resistance mutation K103N against nevirapine to her child.


Subject(s)
Anti-HIV Agents/pharmacology , Drug Resistance, Viral , HIV Infections/transmission , HIV-1/drug effects , Infectious Disease Transmission, Vertical , Nevirapine/pharmacology , Reverse Transcriptase Inhibitors/pharmacology , Drug Resistance, Viral/genetics , Fatal Outcome , Female , HIV Infections/drug therapy , HIV Infections/virology , HIV-1/classification , HIV-1/genetics , Humans , Infant, Newborn , Male , Mutation , Pregnancy , Pregnancy Complications, Infectious/virology
2.
Pregnancy and HIV infection: A european consensus on management.
Coll, Oriol; Fiore, Simona; Floridia, Marco; Giaquinto, Carlo; Grosch-Wörner, Ilse; Guiliano, Marina; Lindgren, Susanne; Lyall, Hermione; Mandelbrot, Laurent; Newell, Marie-Louise; Peckham, Catherine; Rudin, Christoph; Semprini, Augusto E; Taylor, Graham; Thorne, Claire; Tovo, Pier-Angelo.
AIDS ; 16 Suppl 2: S1-18, 2002 Jun.
Article in English | MEDLINE | ID: mdl-12479261

Subject(s)
HIV Infections/therapy , Pregnancy Complications, Infectious/therapy , Anti-HIV Agents/adverse effects , Anti-HIV Agents/therapeutic use , Antiretroviral Therapy, Highly Active/adverse effects , Breast Feeding , Cesarean Section/methods , Child , Child Welfare , Contraception , Counseling , Drug Resistance , Drug Resistance, Viral , Female , Follow-Up Studies , HIV Infections/prevention & control , HIV Infections/transmission , Health Status , Humans , Infant Nutritional Physiological Phenomena , Infant, Newborn , Infectious Disease Transmission, Vertical , Patient Compliance , Postnatal Care/methods , Preconception Care/methods , Pregnancy , Prenatal Care/methods , Zidovudine/therapeutic use
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