ABSTRACT
Thirty-nine percent of 54 phenol face peel patients treated rapidly developed some form of cardiac arrhythmia. When half the face was treated on consecutive days, only 22 percent of 100 patients developed cardiac arrhythmias and these were less severe. Serum phenol levels varied from 4.4 to 337.1 mg/L. Neither age, sex, nor previous cardiac history were accurate predictors of cardiac arrhythmia susceptibility. There was no predictable relationship between serum phenol level and the appearance of cardiac arrhythmia. The duration of the cardiac arrhythmias (2 to 19 minutes) suggests that the risk of cardiac arrhythmia in phenol peeling can be reduced by dividing the face into several units and spacing the application of phenol to each unit 20 minutes apart.
Subject(s)
Arrhythmias, Cardiac/chemically induced , Chemexfoliation/adverse effects , Phenols/adverse effects , Adult , Aged , Arrhythmias, Cardiac/physiopathology , Electrocardiography , Female , Humans , Male , Middle Aged , Phenols/blood , Time FactorsABSTRACT
The derivation of the different phenol formulas for facial rejuvenation is traced. The method of action of phenol and the formula additives is discussed and an improved technique is described with which deep as well as superficial wrinkles of the face can be removed. Phenol chemosurgery is a proper alternative to the surgical face lift in properly selected patients. The potential complications of the procedure should not detract from the benefits.
Subject(s)
Chemexfoliation/methods , Face/surgery , Phenols/therapeutic use , Arrhythmias, Cardiac/chemically induced , Cicatrix/etiology , Ectropion/chemically induced , Erythema/chemically induced , Humans , Nevus, Pigmented/chemically induced , Phenols/toxicity , Pigmentation Disorders/chemically induced , Telangiectasis/chemically inducedSubject(s)
Concurrent Review , Professional Review Organizations , Utilization Review , Rhode IslandSubject(s)
Skin/cytology , Skin/embryology , Glycogen , Histocytochemistry , Humans , Keratins , Lip , Microscopy, Electron , Mucous MembraneSubject(s)
Axilla , Skin , Sweat Glands , Black or African American , Female , Histocytochemistry , Humans , Male , Microscopy, ElectronSubject(s)
Carcinoma, Adenoid Cystic/pathology , Adult , Histocytochemistry , Humans , In Vitro Techniques , Microscopy, ElectronSubject(s)
Urticaria Pigmentosa/pathology , Adult , Female , Humans , In Vitro Techniques , Infant , Male , Mast Cells/pathology , Microscopy, ElectronSubject(s)
Axilla , Skin/cytology , Sweat Glands/cytology , Adult , Black or African American , Female , Glycogen , Humans , Male , Microscopy, Electron , Secretory RateABSTRACT
The formation of the intradermal eccrine sweat duct lumen began in the 15-week-old embryo with a dissolution of the desmosomal attachment plaques, followed by the separation of apposing inner cells and subsequent formation of microvilli at the luminal surfaces. The luminal cells possessed numerous microvilli and crypts and a periluminal band of tonofilaments. In the secretory portion of older embryos (22 weeks old), columnar secretory cells extended from the basement membrane to the luminal border. The presence in these secretory cells of microvilli, Golgi elements, mitochondria, small secretory vesicles, dense secretory granules and abundant endoplasmic reticulum, implies that preparation for secretory functioning begins in embryonic life. The pyramidal myoepithelial cells differentiated from the basal cells seen in younger embryo, and rested upon a basement membrane. In the oldest embryo examined (22 weeks) there was as yet neither intercellular canaliculi nor sufficient difference in the amount of glycogen to enable one to distinguish between dark and light secretory cells. Isolated cilia of 9 + 0 type were occasionally found in the luminal cells of the duct and the secretory segment.
