ABSTRACT
Haematologic and coagulation changes were examined in 60 children whose gestation age was between the 31st and the 39th week and body weight from 950-2650 grams. There were 34 children smaller than they should be for their gestation development, and 26 children whose development correlated with the gestation period. In small children haematologic changes were dominated by polycythaemia with hyperviscosity, thrombocytopenia, reticulosis and leucopenia. The most significant coagulation changes were expressed by prolonged thrombin-time, prothrombin-time and partially thromboplastin-time, decreased fibrinogen with fibrin degradating products, decreased vitamin K factors dependent on coagulation and antithrombin III. In children with normal gestation maturity haematologic and coagulation changes were significantly lower.
Subject(s)
Infant, Small for Gestational Age/blood , Blood Cell Count , Blood Coagulation , Hematocrit , Hemoglobins/analysis , Humans , Infant, NewbornABSTRACT
A group of 30 preterm babies with no evidence of infections was investigated. They were separated in 3 groups according to the gestational age. In the first group, which included babies 28 to 32 weeks of gestational age, haptoglobin was detected in 5, but in 3, levels were under 25 mg/dl. In the second group, which consisted of babies of 33 to 36 weeks of gestational age, haptoglobin was detected in 6 infants, with levels less than 25 mg/dl in 3. Finally, in the group of babies of 37 to 40 weeks, haptoglobin was presented in 7. Haptoglobin was detected in 18 infants, which means in 60% of patients. Levels of haptoglobin were lower in babies of lower gestational age. Values obtained for haptoglobin levels in this study will be used in diagnostic purposes, for comparation with levels obtained in various pathological conditions.
