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Pol J Pharmacol Pharm ; 30(1): 73-5, 1978.
Article in English | MEDLINE | ID: mdl-205846

ABSTRACT

Dibutyryl cGMP, like acetylcholine, shortens and reduces repolarization and overshoot of the action potential, slightly hyperpolarizes the cell and decreases the force of the contraction in the atrial working muscle. It suggests that cGMP may mediate the action of acetylcholine in the atrial working fibres.


Subject(s)
Cyclic GMP/analogs & derivatives , Dibutyryl Cyclic GMP/pharmacology , Heart Atria/drug effects , Acetylcholine/pharmacology , Animals , Depression, Chemical , Myocardial Contraction/drug effects , Rabbits
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