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1.
Ann Anat ; 250: 152152, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37633501

ABSTRACT

BACKGROUND: Compression of the ulnar nerve at the elbow within the cubital tunnel is related to the anatomical structures and is generally believed to be caused by Osborne's ligament (also known as the cubital retinaculum). However, in rare cases an anatomical variation of the developmental peculiarity of a remaining anconeus epitrochlearis muscle may be responsible for the disease. METHODS: We present a series of five cases in which an anconeus epitrochlearis muscle was found as the cause of illness. RESULTS: All patients presented with typical symptoms of numbness and tingling in the hand and ulnar fingers, and recurring pain as well as weakness of the ulnar innervated muscles. With neurophysiologically confirmed diminished nerve conduction velocity and unsuccessful conservative treatment, surgical decompression revealed an anconeus epitrochlearis muscle as the reason of compression. Full symptom relief was achieved immediately after the procedure in all cases. CONCLUSIONS: This article strives to call attention to this entity when diagnosing ulnar nerve compression. Myectomy and medial epicondylectomy is the preferred treatment option in such cases.


Subject(s)
Cubital Tunnel Syndrome , Elbow Joint , Humans , Cubital Tunnel Syndrome/surgery , Cubital Tunnel Syndrome/diagnosis , Cubital Tunnel Syndrome/etiology , Elbow , Muscle, Skeletal/surgery , Ulnar Nerve/surgery
2.
J Plast Reconstr Aesthet Surg ; 72(9): 1555-1563, 2019 09.
Article in English | MEDLINE | ID: mdl-31202696

ABSTRACT

Acellular dermal matrices have recently increasingly been used in alloplastic breast reconstruction with silicone breast implants. Among these matrices, acellular porcine dermis (APD) is frequently applied, but long-term data on tissue integration and capsular fibrosis formation are still missing. Silicone prostheses with (group A) and without (group B) APD as an implant-covering shell were implanted in male Lewis rats. At 3, 12, and 52 weeks after implantation, the constructs were explanted. Molecular biological and immunohistochemical analyses were performed afterwards. On comparing the collagenous layer and the newly formed myofibroblast-rich layer around the implants of both groups, it became apparent that in group A, these layers were thinner, followed by a lower expression of TGFß1 after 12 and 52 weeks. Further, in this group, at the endpoint of 52 weeks, a lower amount of CD68-positive cells in the collagenous and myofibroblast-rich layers were observed and the expression of TNFα was reduced, while the number of Ki67-positive cells was significantly higher with time. Furthermore, MMP1 expression in group A was lower than that in group B, and the calculated ratio of MMP1:TIMP1 expression was higher. The long-term results clearly show a reduction in inflammatory and fibrotic tissue reaction when APD is used to cover silicone prostheses. These experimental data will be of considerable importance for implant-based breast surgery, as they indicate a potential benefit in the reduction of capsular fibrosis formation of an interposition of APD between the recipient and the silicone implant.


Subject(s)
Acellular Dermis , Breast Implantation/methods , Breast Implants , Implant Capsular Contracture/pathology , Mammaplasty/methods , Silicone Gels , Animals , Disease Models, Animal , Fibrosis/genetics , Fibrosis/metabolism , Fibrosis/pathology , Follow-Up Studies , Gene Expression Regulation , Implant Capsular Contracture/genetics , Implant Capsular Contracture/metabolism , Male , Matrix Metalloproteinase 1/biosynthesis , Matrix Metalloproteinase 1/genetics , RNA/genetics , Rats , Rats, Inbred Lew , Swine , Time Factors , Tissue Inhibitor of Metalloproteinase-1/biosynthesis , Tissue Inhibitor of Metalloproteinase-1/genetics
3.
J Obstet Gynecol Neonatal Nurs ; 16(1): 48-55, 1987.
Article in English | MEDLINE | ID: mdl-3643994

ABSTRACT

A series of descriptive studies was carried out to characterize maternal respiration, type of bearing-down efforts, vocalization, and behavior; describe the obstetric conditions and intrauterine pressure associated with the bearing-down reflex; and describe the duration of second stage, fetal heart rate, and neonatal outcomes when women bear down spontaneously. Thirty-one healthy nulliparous women who had received no formal childbirth education were neither directed nor instructed to bear down with contractions. The women were supported in their involuntary bearing-down efforts throughout the second stage of their labors while the above features of their labor were recorded. The findings suggest that labor progress is adequate and fetal outcome is good when the management of the expulsion phase of labor encourages maternal pushing that is complementary with the involuntary bearing-down reflex rather than sustained breath-holding. These findings support the necessity for further research regarding the bearing-down techniques used during labor.


Subject(s)
Labor Stage, Second/physiology , Labor, Obstetric/physiology , Reflex/physiology , Adolescent , Adult , Female , Heart Rate , Heart Rate, Fetal , Humans , Infant, Newborn , Pregnancy , Pressure , Time Factors , Uterine Contraction , Uterus/physiology
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