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1.
Eye (Lond) ; 33(9): 1472-1477, 2019 09.
Article in English | MEDLINE | ID: mdl-30971816

ABSTRACT

BACKGROUND: The etiology of aphakic glaucoma is unclear. It has been suggested that remaining lens epithelium releases cytokines transducing trabecular meshwork cells. Therefore, we compared two cohorts of children undergoing lensectomy. In cohort 1, the entire lens including its capsule was removed, in cohort 2 the peripheral lens capsule was left intact, also to facilitate secondary intraocular lens implantation later on. METHODS: We included children with uni- or bilateral congenital cataract who underwent lensectomy during the first year of life with subsequent contact lenses fitting. Group 1 comprised 41 eyes, group 2 comprised 33 eyes. In group 1, the median age at surgery was 4.0 months in unilateral and 3.0 months in bilateral cases 1, in group 2, 8.1 months and 2.4 months, respectively. The mean follow-up was 12.8 years in group 1 and 9.3 years in group 2. All cases were analyzed for the prevalence of aphakic glaucoma, for visual acuity and for compliance in visual rehabilitation (contact lens/occlusion therapy). RESULTS: We found no significant difference in glaucoma prevalence between group 1 and group 2 (p = 0.68). The overall glaucoma rate was 26% after the mean follow-up of 11 years in both groups. In unilateral cases, the median visual acuity was logMAR 0.7 in both groups. In bilateral cases it was logMAR 0.4 in group 1 and logMAR 0.2 in group 2 (p = 0.05). CONCLUSIONS: Leaving the peripheral lens capsule intact had no negative effect on the incidence of glaucoma and on resulting visual acuity.


Subject(s)
Aphakia, Postcataract/etiology , Cataract Extraction/adverse effects , Cataract/congenital , Glaucoma/etiology , Lens Capsule, Crystalline/surgery , Lens, Crystalline/surgery , Amblyopia/physiopathology , Female , Follow-Up Studies , Humans , Infant , Lens Implantation, Intraocular , Male , Proportional Hazards Models , Risk Factors , Visual Acuity/physiology
2.
South Med J ; 92(5): 459-64, 1999 May.
Article in English | MEDLINE | ID: mdl-10342889

ABSTRACT

BACKGROUND: As managed care organizations (MCOs) continue to expand into the care of the chronically ill, the concept of providing cost-effective care with a preventive approach is vital for primary care providers (PCPs) to embrace. Diabetes is an ideal disease to incorporate this concept. METHODS: We reviewed the literature using MEDLINE. We used the American Diabetes Association (ADA) Provider Recognition Program guidelines as the foundation for MCOs to establish a diabetes disease management program. RESULTS: The implementation of disease management protocols, the use of computerized management systems, and the team approach can provide cost-effective diabetic care. CONCLUSIONS: To compete in the managed care market, it is vital for providers to link with their Independent Practice Associations (IPA), the ADA, and MCOs to implement standard protocols and negotiate for adequate reimbursement.


Subject(s)
Diabetes Mellitus/therapy , Managed Care Programs , Health Planning Guidelines , Humans , Independent Practice Associations , Managed Care Programs/legislation & jurisprudence , Managed Care Programs/trends , Patient Care Team , Therapy, Computer-Assisted
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