ABSTRACT
Possible correlation between Toll-like receptor (TLR)-gene mutations and the susceptibility of the mammary gland to bacterial infections and also the associate breed-dependent aspects of somatic cell concentration (SCC), bacterial infection and TLR-gene mutations in sheep are described. In Polish Lowland Sheep (PLS), milk samples exceeding the level of 500/microL (i.e. 5 x 10(5) per mL) of SCC were recorded almost twice more frequently than in Polish Heath Sheep (PHS) (40 and 22.3%, respectively). The frequency of bacterial infections was also found in a similar ratio (20 and 12.7%, respectively). During detection of the TLR-gene mutation we recorded 2 alleles of TLR1, 6 alleles of TLR2 and 10 alleles of TLR4 genes in PHS sheep, while PLS sheep possessed 2, 4 and 6 alleles, respectively. Statistical analyses revealed a relationship between the specified TLR alleles, SCC and the frequency of incidence of bacterial inflammations of mammary gland. The data may serve as a benchmark for further study of TLR-gene mutation-dependent predisposition of mammary gland defensive cells to recognize the pathogen properly and initiate the immunological response, and may help in identifying one of the markers of natural resistance against sheep mastitis.
Subject(s)
Bacterial Infections/veterinary , Genetic Predisposition to Disease , Mammary Glands, Animal/microbiology , Milk/cytology , Polymorphism, Genetic , Sheep Diseases/genetics , Toll-Like Receptors/genetics , Alleles , Animals , Bacterial Infections/genetics , Gene Frequency , Milk/microbiology , SheepABSTRACT
We evaluated the results of united treatment (thermocoagulation and nafarelin acetate) of the node type of endometriosis) among women with pain syndrome in pelvis minoris. During the treatment we observed withdrawal of pain in lower abdomen among 60% of patients and assuagement in remaining cases. During the treatment by Synarel the menses were absent together with complaints connected with menstruation. The efficacy of the drug together with surgical intervention was many times higher then that of thermocoagulation alone.
Subject(s)
Electrocoagulation/methods , Endometriosis/therapy , Hormones/therapeutic use , Nafarelin/therapeutic use , Pelvic Inflammatory Disease/therapy , Abdominal Pain/diagnosis , Abdominal Pain/etiology , Adult , Endometriosis/complications , Endometriosis/drug therapy , Female , Hormones/administration & dosage , Hormones/chemistry , Humans , Nafarelin/administration & dosage , Nafarelin/chemistry , Pain Measurement , Pelvic Inflammatory Disease/complications , Pelvic Inflammatory Disease/drug therapyABSTRACT
The study involved 69 patients in whom endometriosis was diagnosed. The patients were divided into three groups randomly. In each of the groups, a different method of treatment was applied. In group A thermocoagulation was used, in group B triptorelin was used and in group C the above monitored methods of treatment were applied. Combined therapy involving the use of both thermocoagulation and triptorelin seen to be the most effective.
Subject(s)
Antineoplastic Agents, Hormonal/therapeutic use , Endometriosis/drug therapy , Pelvic Inflammatory Disease/drug therapy , Triptorelin Pamoate/therapeutic use , Adult , Endometriosis/diagnosis , Female , Humans , Middle Aged , Pelvic Inflammatory Disease/diagnosis , Severity of Illness IndexABSTRACT
The investigation group comprised 33 women who, between 1983-2000, passed an operation of removal of endometrial tumors in site of abdominal scars after cesarean section. Among 15 patient routine procedures are performed while among 18 patients the endometrial tumors were enucleated using coagulation. Separation of endometrial tumors which usually does not have a distinct outlines and often infiltrates the surrounding tissues by using coagulation, leads to smaller bleeding and enable the complete excision of the tumor.
Subject(s)
Cesarean Section , Cicatrix, Hypertrophic/surgery , Electrocoagulation/methods , Endometrial Neoplasms/surgery , Postoperative Complications , Abdomen , Adult , Cicatrix, Hypertrophic/pathology , Endometrial Neoplasms/pathology , Female , Humans , Surgical Procedures, Operative/methodsABSTRACT
11 cases of the endometriosis of the appendix vermiformis were analyzed among women in age between 19-57 years. We observed that endometriosis of appendix were accompanied by advanced stages of the ovarian or peritoneum endometriosis in 9 cases. Diagnosis of endometriosis of the appendix is almost impossible before operation because it often could be covered by other genital organs diseases such like: uterine fibromas, ectopic pregnancy, PID. The clinical symptoms of appendicitis observed before an operation seldom find confirmation in results of additional laboratory tests.
Subject(s)
Appendix/surgery , Cecal Diseases/surgery , Endometriosis/surgery , Adult , Appendectomy/methods , Appendix/pathology , Cecal Diseases/pathology , Endometriosis/pathology , Female , Humans , Hysterectomy/methods , Leiomyoma/pathology , Leiomyoma/surgery , Middle Aged , Preoperative Care , Uterine Neoplasms/pathology , Uterine Neoplasms/surgeryABSTRACT
The 15 years old adolescent with a rare mullerian anomaly, uterus unicornis with a rudimentary horn is presented. Patient was 15 years old girl suffered from pelvic pain. In this case we illustrate diagnosis, symptoms and therapy. Patient was submitted complex surgical treatment.
