Is serum protein electrophoresis useful in separating the "high risk group" in patients with colonic polyps?

BACKGROUND: Adenomas have the highest potential or clinical value from among colonic polyps of developing into adenocarcinoma. The aims of this paper are: to establish criteria to identify the high risk group of patients in a group of patients with colonic polyps, to work out a simple scheme for follow-up care after endoscopic polypectomy, and to establish indications for surgery. The usefulness of determination of electrophoresis of serum proteins has been specially analysed to detect early development of malignant growths in patients with colonic polyps regarding alfa-1/alfa-2 and alfa/beta. 67 cases - 21 women, 46 men were tested. Follow-up endoscopy with the electrophoresis was performed after 6 weeks, 6 and 12 months after polypectomy. 97 polyps were resected with endoscopy in 67 patients. 38 patients (39.17%), those constituting the high risk group, were selected. Included were all polyps with grade II and III of cellular differentiation. CONCLUSIONS: 1) alfa-1/alfa-2 and alfa/beta is a helpful test in identifying the high risk group among patients with colonic polyps and it can be used as a screening test, 2) the determination of beta-2-macroglobuline is not useful in the diagnosis of this group of patients, 3) the electrophoresis of proteins should be the first test to perform on patients with colonic polyps. The relation of electrophoresis to endoscopic polypectomy aids evaluations of patients specially predisposed to malignant.

[Insulinoma exclusively localized during intraoperative ultrasonography]. / Insulinoma zlokalizowany wylacznie podczas ultrasonografii sródoperacyjnej.

The case of the patient surgically treated for diagnosed pancreatic insulinoma is reported. Pancreatic insulinomas are the most often diagnosed hormonally active tumors of pancreas. They are small in size, localized evenly in the head, body or tail of pancreas. Their precise location is not easy. This case confirms that the preoperative localization of the tumor is very difficult and preoperative image tests often fail. The performance of intraoperative ultrasonography (IOUS) led to the visualization of the tumor and the curative surgery.

[Instillagel in prevention of postoperative urinary tract infection--randomized trial]. / Instillagel w profilaktyce pooperacyjnych zakazen ukladu moczowego. Badanie randomizowane.

UNLABELLED: The progress of operative technique, introduction of new drugs, modernizing of medical equipment are the cause of long and complicated operations. For that reason, the number of patients, who need the catheterization of the urinary bladder is increasing. The use of the vesical catheter over 5 days is the cause of the urinary tract infection (bacterial and mycotic), the bacteraemia and the extension of the time of recovery. The aim of the study was the estimation of the usefulness of the preparation Instillagel used at the time of the urinary bladder catheterization in the patients before an operation, in aspect of frequency of urinary tract infection. Between January and December 2000, 59 patients were selected for the study. The patients were divided into two groups. In the first group, the preparation Instillagel was used at the time of the catheterization. In the control group 2% Lignocainum hydrochloricum was used at the time of the catheterization. The study was prospective and randomized. The usefulness of the preparation Insillagel was estimated through the comparison of frequency of the urinary tract infection in both groups. The catheterization of the urinary bladder was performed according to aseptic principle. The difference between number and age of the patients in both groups was not statistically significant (p = 0.8538). The time of the keeping of the vesical catheter was similar in both groups (p = 0.576635). The urinary tract infection estimated on the basis of clinical symptoms and laboratory findings was diagnosed in 13 patients (5 patients in the first group, and 8 patients in the control group). The frequency of urinary tract infection was not statistically significant in both groups. CONCLUSIONS: The urinary tract infection is frequent complication in patients with catheter in the urinary bladder, before operation. The frequency of urinary tract infection was not statistically significant in both groups. The discomfort and pain occurred with the same frequency in both groups.