[An attempt to choose the optimal antibiotic for early treatment of neonates with bacterial sepsis]. / Próba doboru optymalnego antybiotyku do wstepnego leczenia noworodków z posocznicami bakteryjnymi.

Aim of our study was making easier choice of right antibiotic to treatment newborns with sepsis after receiving results of bacteriological test. We analysed antibiograms that were results of first bacteriological test of blood samples taken from 59 neonates, who were admitted in first week of life to the Neonatal Pathology Clinic in Zabrze. On the ground of our analysis we propose applying netilmicin and cephalotin in every case of neonate with symptoms suggesting the sepsis. These two antibiotics have the best effects in treatment the sepsis.

[Usefulness of a scoring system based on selected hematologic values in early diagnosis of neonatal bacterial infections]. / Przydatnosc systemu punktowego opartego na wybranych wartosciach hematologicznych w diagnostyce wstepnej zakazen bakteryjnych u noworodków.

The aim of our work is to estimate usefulness of morphological blood tests, as simple to make and easy to estimation, in screening diagnostics of neonatal infections. We chose the following indications for estimation, as possible to obtain in every hospital: total leucocyte count, total neutrophil count, total immature neutrophil count, total thrombocyte count, ratio of immature neutrophil count to total neutrophil count (I : T), ratio of immature neutrophil count to mature ones. We examined 143 newborns admitted to the Neonatal Pathology Clinic in Zabrze in first week of life, divided into three groups: with sepsis, with suspicion of sepsis, and without infection. We assume that deviation of (at least) three indicators or two (necessary with I : T) is incorrect result. We obtain sensitivity: 54.35% for sepsis, 50% for suspicion of sepsis, and 52,70% for both groups (together with infection), and specificity 98.55%. We consider that our haematological scoring system is helpful in early diagnostics of neonatal bacterial infections.

[Evaluating the usefulness of qualitative analysis of latex c-reactive protein for diagnosing neonatal sepsis]. / Ocena przydatnosci analizy jakosciowej bialka c-reaktywnego metoda lateksowa przy uzyciu crp latex quick test firmy dialab w diagnostyce zakazen bakteryjnych u noworodków.

We analyzed the results of determinations C-reactive protein (Latex Test Dialab firm) of 136 newborns. We divided them into three groups: with generalized infections, with infection without sepsis and without infection. Sensitivity of method for neonates with septicaemia was 60%, for neonates with infection without sepsis--81.25%, together for all infections--66.1%. After overlooking sepsis caused by Staphylococcus epidermidis sensitivity for sepsis was 81.8% and for all infections--81.6%.