Evidence for involvement of ketoglutarate in the biosynthesis of Canthin-6-one from cell cultures of Ailanthus altissima.

(13)C enrichments at C-3, C-4, C-5 and C-6 of canthin-6-one from cell cultures of Ailanthus altissima supplemented with [1-(13)C], [2-(13)C] and [1,2-(13)C] acetate, give evidence of the involvement of ketoglutarate as an intact precursor in the biosynthetic pathway.

Indole-3-lactic acid as a tryptophan metabolite produced by Bifidobacterium spp.

Fifty-one strains of the genus Bifidobacterium have been found to accumulate indole-3-lactic acid in culture broth. The isolated metabolite was identified through mass and nuclear magnetic resonance spectroscopy. All the microorganisms tested, as resting cells, have been shown to be able to convert L-tryptophan into L-indole-3-lactic acid.