1.
J Ethnopharmacol
; 20(1): 21-4, 1987 Jun.
Article
in English
| MEDLINE
| ID: mdl-3626592
ABSTRACT
(+)-Gossypol has neither antifertility effect nor toxicity at the dosage of 30 mg/kg orally for 14 days in male rats, but slight damage was found in the germinal epithelium of the testis in animals dosed for 4 weeks. (-)-Gossypol at 30 mg/kg orally for 7 days clearly had an antifertility effect in male rats. It appears that (-)-gossypol is the active stereoisomer of racemic gossypol.
Subject(s)
Gossypol/toxicity , Infertility, Male/chemically induced , Animals , Male , Rats , Rats, Inbred Strains , Sperm Motility/drug effects , Stereoisomerism
2.
Zhong Xi Yi Jie He Za Zhi
; 6(9): 530-2, 515, 1986 Sep.
Article
in Chinese
| MEDLINE
| ID: mdl-2947723