ABSTRACT
The examination of 2033 patients with severe mechanical injuries has shown that early intoxication takes place in 30.3% of the patients. Patients with blood loss of 35-40% and more, receiving more than 1 l of preserved blood make a group of high risk. Intoxication was more frequent in patients with one localization of injury when it is an injury of extremities or abdomen. In associated injuries the development of intoxication is determined by localization and kind of the main injury and is dependent on association with severe traumas of the extremities and abdomen.
Subject(s)
Toxemia/etiology , Wounds and Injuries/complications , Blood Group Incompatibility/complications , Hemorrhage/complications , Hemorrhage/therapy , Humans , Time Factors , Transfusion ReactionABSTRACT
The examination of 2033 patients with severe mechanical injuries has shown that in most patients with traumas of the head, chest and upper extremities of the same localization (isolated or multiple) the volume of blood loss was not more than 20% of the circulating blood volume. Isolated and multiple injuries of the abdomen, pelvis, spine and lower extremities in 28-54% of the patients were followed by blood loss more than 20% of the circulating blood volume. Associated traumas in most cases were followed by massive blood loss (more than 40% of the CBV).
Subject(s)
Blood Volume , Hemorrhage/physiopathology , Wounds and Injuries/complications , Abdominal Injuries/physiopathology , Adult , Blood Volume Determination , Craniocerebral Trauma/physiopathology , Hematocrit , Humans , Middle Aged , Thoracic Injuries/physiopathologySubject(s)
Pancreas/injuries , Critical Care , Hemorrhage/etiology , Hemorrhage/surgery , Humans , Pancreatic Diseases/etiology , Pancreatic Diseases/surgery , Pancreatitis/etiology , Pancreatitis/surgery , Shock, Traumatic/etiology , Shock, Traumatic/therapy , Wounds, Nonpenetrating/complications , Wounds, Penetrating/complicationsABSTRACT
Associated injuries of the abdomen result in peritonitis twice more often than isolated ones, the peritonitis having more severe course and being the cause of lethal outcomes in 57% of the victims. The immune deficient state is thought to be one of the causes responsible for the reduced resistance to infection and the development of peritonitis in the postshock period. Patients with associated traumas show a considerable inhibition of the immune system within several hours and an impairment of its regulation which grows during the next day. So, even at the early terms the operative methods must be similar to those used in operations for the developed peritonitis.
Subject(s)
Abdominal Injuries/physiopathology , B-Lymphocytes/immunology , Growth Hormone/metabolism , Peritonitis/etiology , T-Lymphocytes/immunology , Abdominal Injuries/complications , Adult , Female , Humans , Leukocyte Count , Lymphopenia/complications , MaleABSTRACT
On the basis of the many-years clinico-physiological investigations the authors substantiate the idea of the trauma disease, its forms and periods of its development.
Subject(s)
Shock, Traumatic/etiology , Wounds and Injuries/complications , Homeostasis , Humans , Hypoxia/etiology , Respiratory Insufficiency/etiology , Shock, Traumatic/physiopathology , Toxemia/etiology , Wounds and Injuries/physiopathologyABSTRACT
The characteristics of peculiarities of a car trauma in 788 cases is presented. A multiple and combined character of injuries with a severe clinical picture (72.4%) is emphasized. The attention is drawn to leading and frequent severe sequelae of the trauma: massive blood loss (55.6%), disturbance of external respiration (56.7%), injuries to vitally important organs (54.7%), which constitute main causes of fatal outcome in acute period (25.9%). The difficulties, one encounters during the treatment of such injuries, are listed and the conclusion is drawn that the treatment of car injuries should be carried out in a specialized department with the participation of broadly qualified surgeons and reanimatologists.
