ABSTRACT
The preparation "melagenin" stimulating reproduction of melanocytes and synthesis of melanotic pigment was isolated from human placenta in Cuba. As many as 366 pediatric patients with vitiligo who ranged from 4 to 15 years old were followed up for 1 year. In 62 cases the area of depigmentation amounted to 71 to 100%. Treatment with melagenin proved to be effective in 83% of vitiligo patients. Indications and contraindications have been determined.
Subject(s)
Lipoproteins/therapeutic use , Placental Extracts/therapeutic use , Vitiligo/drug therapy , Adolescent , Child , Child, Preschool , Chronic Disease , Drug Evaluation , Humans , Time Factors , UkraineABSTRACT
A total of 300 patients with atopic dermatitis were examined for the status of their gastrointestinal tract, liver and pancreas functioning. Besides clinical and laboratory studies, ultrasonic scanning of the liver and pancreas, fibrogastroduodenoscopy, radioimmunoassay of serum trypsin, C peptide, insulin, cholylglycine, radionuclide hepatography, and gamma pancreatoscintigraphy were carried out. Analysis of the findings permit a conclusion that chronic pancreatitis and impaired function of the liver and bile excretion are quite frequent in atopic dermatitis patients.