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J Clin Pharm Ther ; 33(4): 451-2, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18613863

ABSTRACT

Colchicine is widely used, primarily for the treatment of gouty arthritis and familial Mediterranean fever. Colchicine intoxication is a rare but potentially life-threatening event. Herein, we reported a 26-year-old woman who presented to the emergency department after ingesting 27.5 mg of colchicine in a suicide attempt. She exhibited signs typical of colchicine-poisoning and developed infectious complications but with subsequent complete recovery. This paper discusses the role of colchicine poisoning in increasing susceptibility to infections. This aspect is usually under-appreciated in the clinical picture of colchicine overdose.


Subject(s)
Colchicine/poisoning , Gout Suppressants/poisoning , Infections/etiology , Adult , Drug Overdose , Emergency Treatment , Female , Humans , Suicide, Attempted
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