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Tsitologiia ; 19(9): 1000-5, 1977 Sep.
Article in Russian | MEDLINE | ID: mdl-303824

ABSTRACT

A correlation between macro- and micronuclear lymphocytes and their DNA metabolism was studied in the lymph nodes of BALB/c mice during the growth of methylcholanthrene sarcoma. The number of macronuclear lymphocytes was seen reduced along with a simultaneous increase of 3H-thymidine indices in regional lymph nodes during the tumor growth. The number of micronuclear lymphocytes of these lymph nodes was accordingly increasing. In distant lymph nodes the reaction was significantly less expressed.


Subject(s)
DNA/metabolism , Lymph Nodes/metabolism , Lymphocytes/metabolism , Sarcoma, Experimental/metabolism , Animals , Autoradiography , B-Lymphocytes/metabolism , Male , Methylcholanthrene , Mice , Mice, Inbred BALB C , Sarcoma, Experimental/chemically induced , T-Lymphocytes/metabolism , Thymidine/metabolism
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