ABSTRACT
We describe one patient with acute Epstein-Barr virus (EBV) infection associated with severe thrombocytopenia and review 36 additional cases reported in the literature. Complications of EBV infection due to severe thrombocytopenia occurred in 10 (27.0%) of 37 patients, and 2 (5.4%) of 37 patients died. Although acute EBV infections are generally benign and self-limiting, thrombocytopenia, a potentially serious complication, should not be overlooked.
Subject(s)
Herpesviridae Infections/complications , Herpesvirus 4, Human , Thrombocytopenia/complications , Tumor Virus Infections/complications , Acute Disease , Adolescent , Female , Herpesvirus 4, Human/isolation & purification , Humans , Severity of Illness IndexABSTRACT
Strongyloides stercoralis usually causes chronic asymptomatic infection in humans. However, in patients with AIDS, malignancy, and individuals receiving corticosteroids, disseminated infection can develop, associated with an extremely high mortality rate and frequent treatment failure with thiabendazole. Recently, ivermectin was found to be very effective in such patients. The authors report a case of strongyloidiasis in a patient with hypogammaglobulinemia in which ivermectin failed to clear Strongyloides larvae from stool, despite repeated courses of treatment throughout 14 months.
