ABSTRACT
In this paper, we present the results of non-invasive blood glycaemia measurements. The blood used in the measurements was calf blood. The measurement method uses an electromagnetic sensor based on eddy currents, which allows the detection of blood glycaemia levels through the variation of the dielectric parameters of the blood. A change in blood glucose concentration causes a variation in the dielectric parameters, in particular conductivity. Detection is only possible at a resonant frequency. The measurements were taken in a static and dynamic state (with and without circulation of blood). The blood is inside a plastic tube placed within the sensor and is surrounded by gelatine, which simulates muscular tissue. The plastic tube simulates the vein where blood circulation occurs. The in vitro results in both cases (static and dynamic) are provided. Under unfavourable conditions we can detect a change of +/- 2 g/l of glucose. We present and discuss these results.
Subject(s)
Biosensing Techniques/instrumentation , Blood Glucose Self-Monitoring/instrumentation , Blood Glucose/analysis , Electromagnetic Phenomena/instrumentation , Glucose Metabolism Disorders/diagnosis , Animals , Biosensing Techniques/methods , Blood Glucose Self-Monitoring/methods , Cattle , Electromagnetic Phenomena/methods , Equipment Design , Equipment Failure Analysis , Humans , Magnetics/instrumentation , Reproducibility of Results , Sensitivity and Specificity , TransducersABSTRACT
In this paper, we develop a non-invasive method to measure glycaemia levels. The method is based on an electromagnetic sensor associated with a specific electronic card. Results obtained on whole pig blood show the influence of the temperature and the linearity between the glucose concentration and the process card signal output. Measurements are reproducible and the resolution obtained permits determination of the glucose level around 0.1 g l(-1).