[Tumor-like amyloidosis of the parotid : A case report].

INTRODUCTION: Tumor-like amyloidosis or amyloïdoma is a nodular lesion related to abundant amyloid deposits that can clinically mimic a malignant tumor. Its etiologic diagnosis requires searching an underlying infectious disease, a connective tissue disorder or a lymphoma. Parotid amyloïdoma is exceptional, and only four cases have been reported in the literature from 1988 to 2021 (PubMed research). CASE REPORT: We reported the case of a 60-year-old, diabetic and hypertensive woman, presenting an isolated swelling of the right parotid region without facial paralysis or cervical lymphadenopathy. A right superficial parotidectomy with a frozen section examination was performed. Histologically, the swelling was related to abundant amyloid deposits without tumor. On immunohistochemistry, amyloidosis was type AA. The association with the Sjögren's syndrome was confirmed. CONCLUSION: The association of parotid amyloïdoma with Sjögren's syndrome is a rare condition. The histologic diagnosis may be difficult in this case. Therefore, it is necessary in the case of amyloïdoma to confirm the diagnosis and carry out an etiological investigation to search for an underlying pathology.

Adult Still's disease and squamous cell carcinoma in a 69-year-old woman.

Adult-onset Still's disease (AOSD) has been recognized as a cause of fevers of unknown origin. Malignancies are the most important differential diagnoses of AOSD which has been rarely reported in association with cancer. The present paper undertakes the study of a 69-year-old Tunisian woman with AOSD according to the diagnostic criteria of Yamaguchi. She was treated by prednisone, then associated with methotrexate. 18 months later, she developed a squamous cell carcinoma treated with chemotherapy and radiotherapy.

Deep vein thrombosis of the left arm revealing an asymptomatic pulmonary tuberculosis.

Although not frequent, thromboembolic events occurring in patient presenting tuberculosis may be observed. Frequency of such thromboembolic events seems correlated with the severity of tuberculosis. We herein report a case of venous thrombosis revealing an asymptomatic tuberculosis. A man aged 32 years was admitted for deep and superficial vein thrombosis of the left arm. Chest CT angiography ruled out pulmonary embolism and showed a mediastinal and pulmonary heterogeneous necrotic mass at the apical segment of the left lung. Histological study of a CT scan-guided pulmonary biopsy showed signs of caseating granuloma compatible with tuberculosis. Diagnosis of venous thrombosis due to pulmonary tuberculosis with lymph nodes involvement was made. Antituberculosis treatment was initiated and required an adjustment of anticoagulant therapy. Our observation highlights the possibility of causative effect between tuberculosis and venous thrombosis.