ABSTRACT
Since an increased incidence of occlusive vascular disease has been reported in psoriasis, serum levels of apolipoproteins AI, AII and B were determined in 61 patients with the disease and compared with that of 34 healthy controls. No significant differences were found between the two groups. These findings suggest that the occurrence of thromboembolic disorders in psoriasis is not related to altered levels of apolipoproteins AI, AII, B in these patients.
Subject(s)
Apolipoproteins A/blood , Apolipoproteins B/blood , Lipoproteins, HDL/blood , Psoriasis/blood , Adolescent , Adult , Aged , Apolipoprotein A-I , Apolipoprotein A-II , Female , Humans , Male , Middle AgedSubject(s)
Chromosome Aberrations/genetics , Keratosis/genetics , Pigmentation Disorders/genetics , Adult , Chromosome Disorders , Humans , Male , SyndromeABSTRACT
Eruptive vellus hair cyst and steatocystoma multiplex are infrequent lesions. Although there are clinical similarities between both entities, histologic features are distinctive. Especially noteworthy is the presence of sebaceous glands within the cyst wall of steatocystoma. We describe herein a patient with a familial monomorphous papular eruption on the forehead, biopsies from which showed features of both eruptive vellus hair cyst and steatocystoma multiplex.
Subject(s)
Cysts/pathology , Epidermal Cyst/pathology , Hair , Skin Diseases/pathology , Adult , Biopsy , Female , Humans , Skin Diseases/geneticsSubject(s)
Epidermal Cyst/pathology , Hair Diseases/pathology , Adult , Epidermal Cyst/genetics , Female , Hair Diseases/genetics , HumansABSTRACT
Four cases of familial mucocutaneous candidiasis corresponding to two families were studied. In two of the cases (Family I), there were lesions in the mouth, vaginal mucosa, nails, palms and soles, with no other associated infections. In the other two cases (Family II) there were oral (glossitis with macroglossia), genital and inguinal folds lesions, associated to frequent bacterial infections (recurring forunculosis , pneumonia). The immunological study in the four cases showed overlapping results: anti-candida circulating antibodies at high dilutions, a negative or weakly positive candidine a negative TTL to candida in some of the cases, and not other abnormalities in T. lymphocytes. All of the cases became sensitive to DNCB. In two of them, there were low figures of ferritin (Family II); however, no improvement was obtained with an iron treatment. There were no endocrinological abnormalities in any case. All of the cases were cured with ketoconazole in a few months, and no relapse was found six months after the end of the treatment in one of them. A follow up could not be performed on the other three cases.
