ABSTRACT
Mycoplasma spp. are rarely recognized agents of infective endocarditis. We report a case of Mycoplasma hominis prosthetic valve endocarditis diagnosed by 16S ribosomal DNA (rDNA) PCR and culture of valves in a 74-year-old man. We reviewed the literature and found only 8 other cases reported.
Subject(s)
Endocarditis/diagnosis , Endocarditis/pathology , Mycoplasma Infections/diagnosis , Mycoplasma Infections/pathology , Mycoplasma hominis/isolation & purification , Prosthesis-Related Infections/diagnosis , Prosthesis-Related Infections/pathology , Aged , Anti-Bacterial Agents/pharmacology , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , Endocarditis/microbiology , Humans , Male , Microbial Sensitivity Tests , Molecular Sequence Data , Mycoplasma Infections/microbiology , Mycoplasma hominis/classification , Mycoplasma hominis/drug effects , Mycoplasma hominis/genetics , Prosthesis-Related Infections/microbiology , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNAABSTRACT
Guillain-Barré syndrome (GBS) is an autoimmune disease that can be triggered by different infectious agents. Here we report the case of a 26-year-old Algerian woman who developed GBS associated with a Mycobacterium bovis cervical lymphadenitis. Following intravenous immunoglobulin therapy, the patient's neurologic state returned to normal after 3 months. The lymphadenitis responded more slowly to the antituberculous treatment and an excision of necrotic cervical lymph nodes had to be performed four times. Antibiotics were administered for 16 months: ethambutol was stopped after 2 months, and rifampicin and isoniazid pursued for 14 months. An extensive etiological investigation showed that, in this case, the only likely infectious trigger GBS was the concomitant M. bovis infection. To our knowledge, this is the first report of GBS triggered by M. bovis. We performed a literature review revealing that the association between tuberculosis and Guillain-Barré syndrome is very rare (only seven cases previously reported) but is not coincidental. Physicians should be aware that tuberculosis can be a cause of GBS.
Subject(s)
Guillain-Barre Syndrome/diagnosis , Mycobacterium bovis/isolation & purification , Tuberculosis, Lymph Node/complications , Adult , Antitubercular Agents/therapeutic use , Debridement , Female , Guillain-Barre Syndrome/therapy , Humans , Immunoglobulins, Intravenous/therapeutic useABSTRACT
We described two cases of acalculous cholecystitis (AAC), due to EBV primary infection in two young Caucasian women and we reviewed other reported cases. In contrast with AAC of other etiologies, antibiotics and surgery are not useful in the management of AAC secondary to EBV.
