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1.
Khirurgiia (Mosk) ; (4): 30-36, 2019.
Article in Russian | MEDLINE | ID: mdl-31120444

ABSTRACT

AIM: To optimize surgical care for the hemorrhagic colorectal cancer. MATERIAL AND METHODS: 77 patients diagnosed with hemorrhagic colorectal cancer were reviewed: 9 patients of them were efficaciously treated with conservative therapy (I group); 47 - underwent successful endoscopic coagulation (I); 4 - arterial embolization (I), 2 - ligation of internal iliac arteries (I), 15 - acute resection (II group). 20 of 62 patients I group underwent plan surgery and radiation or chemotherapy during 7-10 days after hemostasis and normalization hemoglobin. The 3-year cumulative survival after resections (acute versus plan) was plotted on a Kaplan-Meier chart in 31 patients. RESULTS: Complications and postoperative mortality was significantly higher after acute resection (II group) compared with plan resection (I): 33,3% vs 20%; 15% vs 5%, respectively. The survival rate was higher after plan than acute resections: 0,8882 and 0,3571, respectively. CONCLUSION: Acute surgery for hemorrhagic colorectal cancer should only be carried out by appropriately trained surgeons in multi-specialty hospital. Endoscopy and arterial embolization are the most effective means of successfully controlling hemorrhage while minimizing potential complications. A bridging strategy may be a valid alternative in some of patients with hemorrhagic colorectal cancer, because a significantly lower postoperative mortality rate.


Subject(s)
Colorectal Neoplasms/surgery , Gastrointestinal Hemorrhage/therapy , Colorectal Neoplasms/complications , Colorectal Neoplasms/mortality , Embolization, Therapeutic , Endoscopy , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/mortality , Gastrointestinal Hemorrhage/surgery , Humans , Retrospective Studies
2.
Khirurgiia (Mosk) ; (1): 53-59, 2019.
Article in Russian | MEDLINE | ID: mdl-30789609

ABSTRACT

AIM: To standardize surgical care for malignant colonic obstruction. MATERIAL AND METHODS: There were 572 patients with malignant colonic obstruction: 247 of them were hospitalized in 2011-2013 (I group); 325 - in 2014-2017 (group II). Forty-six patients underwent medication; 302 - acute resection; 141 - stoma construction; 83 - stent deployment. Elective surgery and radiation or chemotherapy was performed after 0.5-6 months in 110 patients of group II. Acute resection was more common in I group, elective resection - in group II. Early and long-term results including Kaplan-Meier 3-year overall survival were compared in both groups. RESULTS: Complications occurred in 46.69% (group I) and 21% (group II). Postoperative mortality was significantly higher in group I compared with II group: 26.11 and 10.33%, respectively. Three-year overall survival was higher in group I compared with group II: 0.82 and 0.69, respectively. CONCLUSION: Advisability of new two-stage surgical standard is confirmed for malignant colonic obstruction. Stoma formation and stenting may be a valid alternative in some patients with malignant colonic obstruction due to significantly lower postoperative mortality.


Subject(s)
Colonic Neoplasms/therapy , Digestive System Surgical Procedures/standards , Intestinal Obstruction/therapy , Antineoplastic Agents/administration & dosage , Chemotherapy, Adjuvant , Colectomy , Colonic Neoplasms/complications , Colonic Neoplasms/mortality , Colostomy , Digestive System Surgical Procedures/adverse effects , Humans , Intestinal Obstruction/etiology , Intestinal Obstruction/mortality , Kaplan-Meier Estimate , Prosthesis Implantation , Radiotherapy, Adjuvant , Stents
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