Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Public Health Nutr ; 15(10): 1827-34, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22244458

ABSTRACT

OBJECTIVE: To assess classical and non-classical metabolic risk biomarkers in prepubertal children with different levels of cardiorespiratory fitness (CRF). DESIGN: CRF was assessed by the 20 m shuttle run test. To estimate physical activity, participants were observed while engaged in an after-school programme. Additionally, a short test based on a validated questionnaire was used to obtain information about physical activity practice and sedentary habits. Anthropometric parameters, blood pressure, and classical and non-traditional metabolic risk biomarkers--plasma lipid profile, glucose and insulin, homeostasis model assessment-insulin resistance index (HOMA-IR), plasma uric acid, transaminases and C-reactive protein (CRP)--were measured. SETTING: The study was conducted in local elementary schools in Córdoba, Spain. SUBJECTS: One hundred and forty-one healthy children (eighty-eight boys, fifty-three girls) aged 7-12 years, in Tanner stage I, were recruited. They were divided into two groups after they performed the 20 m shuttle run test: equal or higher cardiovascular fitness (EHCF) group and low cardiovascular fitness (LCF) group. RESULTS: The LCF group displayed significantly higher TAG (P = 0.004) and lower HDL cholesterol levels (P = 0.001), as well as significantly lower values for the non-traditional lipid marker apo-A1 (P = 0.001) compared with the EHCF group. The LCF children displayed higher plasma glucose (P = 0.003) and insulin levels, higher HOMA-IR scores (P < 0.001) and higher plasma uric acid and CRP levels (P < 0.05). After adjustment for BMI, age and sex, no statistically significant differences were found between groups for the biomarkers analysed. CONCLUSIONS: The study provides new information to understand the role not only of weight status but also of the level of CRF on the metabolic health profile of prepubertal children.


Subject(s)
Exercise Test , Obesity/physiopathology , Physical Fitness/physiology , Biomarkers/blood , Biomarkers/metabolism , Blood Glucose/metabolism , Body Mass Index , C-Reactive Protein/metabolism , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/metabolism , Child , Female , Humans , Insulin/blood , Insulin Resistance , Lipids/blood , Male , Metabolic Syndrome/metabolism , Obesity/blood , Obesity/metabolism , Risk Factors , Spain
2.
Eur J Appl Physiol ; 106(2): 181-6, 2009 May.
Article in English | MEDLINE | ID: mdl-19224242

ABSTRACT

Intense aerobic exercise has been found to prompt changes in oxidative stress, but in children remains almost unexplored. The aim was to investigate the effect of intense physical exercise on reduced glutathione (GSH as a biomarker of oxidative stress) and adrenocortical response (to verify a certain level of stress after exercise) in 38 prepubescent and 32 pubescent non-athlete boys. Four subgroups were established as puberty stage and physical fitness. Saliva samples were taken before and after incremental exercise testing to measure GSH, and cortisol levels. Saliva reduced glutathione levels were lower in all subgroups after exercise except in the prepubescent average fit group, significance being greater in the pubescent (P < 0.001) than in the prepubescent group (P < 0.01). Saliva cortisol increased after exercise in all except in the prepubescent "average fit" group. Physical exercise may give rise to oxidative stress and adrenocortical response in pubescent and prepubescent boys, depending on the duration and intensity of the test.


Subject(s)
Exercise/physiology , Glutathione/metabolism , Saliva/chemistry , Animals , Body Mass Index , Child , Exercise Test , Humans , Hydrocortisone/metabolism , Male , Oxidative Stress , Oxygen/metabolism
SELECTION OF CITATIONS
SEARCH DETAIL
...