ABSTRACT
AIM: Describe the severity of bone lesion and evaluate the results of the treatment of osteomyelitis in patients with sickle cell disease. MATERIAL AND METHODS: It was about a prospective study done from December 2005 to November 2006 in patients with confirmed sickle cell admitted for osteomyelitis. RESULTS: We gather together 62 cases of osteomyelitis in sickle cell disease among 120 cases, which was about 51.7%. The mean age has been 17 years. The diagnosis was made on biology and x rays. 46.78% of our patients were sickle cell homozygote. Bone pain was the 1st reason of consultation with 53.2% of cases. Staphylococcus aureus and salmonella were the most frequent germs, with 43.55% each. Complications were noted in 32.26% because of diagnosis delay (P 0.05). Delay in the management or incorrect treatment can result in a severe and definitive sequel for the functional future of those patients.
Subject(s)
Anemia, Sickle Cell/epidemiology , Osteomyelitis/diagnosis , Adolescent , Adult , Child , Female , Humans , Male , Mali/epidemiology , Osteomyelitis/microbiology , Osteomyelitis/therapy , Prospective Studies , Young AdultABSTRACT
Objectifs : Decrire la gravite de l'atteinte osseuse et evaluer les resultats du traitement de l'osteomyelite drepanocytaire. Materiel et methodes : Il s'agissait d'une etude prospective allant deDecembre 2005 a Novembre 2006 se rapportant sur les malades admis pour osteomyelite pour causede drepanocytose confirmee. Resultat : Nous avons collige 62 cas d'osteomyelite d'originedrepanocytaire sur 120 cas d'osteomyelite; soit 51;7. L'age moyen a ete de 17 ans. Le diagnostic arepose sur la biologie et l'imagerie. 46;78de nos malades etaient drepanocytaires homozygotes. Ladouleur osseuse a ete le premier motif de consultation avec 53;2des cas. Le staphylocoque dore et lesalmonella ont ete les germes les plus frequents; soit 43;55pour chacun. Les complications ont ete notees chez 32;26dues au retard diagnostique (P 0;05). Le retard dans la prise en charge ou un traitement inadapte peut aboutir a des sequelles graves et definitives pour l'avenir fonctionnel de ces malades