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2.
Rev Port Cardiol (Engl Ed) ; 39(3): 137-149, 2020 Mar.
Article in English, Portuguese | MEDLINE | ID: mdl-32340853

ABSTRACT

INTRODUCTION: Infective endocarditis (IE) is a serious disease with significant in-hospital mortality (15-30%) despite advances in medical and surgical therapy. AIMS: To perform a clinical characterization of patients undergoing cardiac surgery for IE and to identify factors that predict in-hospital mortality. METHODS: We retrospectively analyzed 145 patients with IE admitted between January 2006 and October 2017. RESULTS: The median age was 72 years. IE was acquired mainly in the community (69%), and involved the native aortic valve in 54% of patients, biological prosthetic valves in 22.1% and mechanical valves in 10.3%. Staphylococcus spp. (31.0%) were the most frequent etiological agents. Cardiac surgery was emergent in 29 patients, urgent in 108, and elective in eight. The main indications were heart failure (57.9%), large vegetations (20%), systemic embolism (17.2%) and valve dysfunction (15.2%). Overall, biological valves were implanted in 62.1% of patients and mechanical valves in 37.2%. A total of 19 patients (13.1%) died. Predictors of mortality were preoperative atrial fibrillation and lower left ventricular ejection fraction, postoperative severe valve regurgitation associated with cardiogenic shock, sepsis, septic shock associated with cardiogenic shock, cardiac tamponade, need for renal replacement therapy and, although without statistical significance, emergent surgery. CONCLUSIONS: There is a need for better indicators to enable early identification of surgical candidates for IE, implementation of a heart team, and better surgical strategies, including more rapid intervention, more specific postoperative care, and optimal antibiotic therapy.


Subject(s)
Aortic Valve/surgery , Cardiac Surgical Procedures/methods , Endocarditis/surgery , Heart Valve Prosthesis/adverse effects , Hospital Mortality/trends , Aged , Aged, 80 and over , Aortic Valve/microbiology , Aortic Valve/pathology , Atrial Fibrillation/epidemiology , Atrial Fibrillation/etiology , Atrial Fibrillation/mortality , Cardiac Surgical Procedures/statistics & numerical data , Case-Control Studies , Endocarditis/microbiology , Endocarditis/mortality , Endocarditis/pathology , Female , Heart Failure/epidemiology , Heart Failure/mortality , Heart Failure/surgery , Heart Valve Prosthesis/statistics & numerical data , Humans , Male , Middle Aged , Predictive Value of Tests , Prognosis , Prosthesis-Related Infections/complications , Retrospective Studies , Shock, Cardiogenic/epidemiology , Shock, Cardiogenic/etiology , Shock, Cardiogenic/mortality , Staphylococcus/isolation & purification , Ventricular Dysfunction, Left/epidemiology , Ventricular Dysfunction, Left/etiology , Ventricular Dysfunction, Left/mortality
3.
Arq. bras. cardiol ; 111(3 supl.1): 173-173, set., 2018.
Article in Portuguese | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1026645

ABSTRACT

As lesões da valva tricúspide decorrentes de trauma torácico fechado são raras e frequentemente subdiagnosticadas. Relata-se o caso de paciente do sexo masculino de 42 anos de idade com sinais e sintomas de insuficiência cardíaca direita e fibrilação atrial (FA) persistente em anticoagulação oral com Varfarina. A história revelou trauma torácico há aproximadamente 11 anos, evoluiu com insuficiência tricúspide importante, disfunção biventricular e taquicardiomiopatia secundária à FA. Realizou-se efetivamente cirurgia cardíaca de troca valvar tricúspide com prótese biológica, sem intercorrências no pós-operatório imediato. O momento ideal para intervenção cirúrgica na insuficiência tricúspide traumática ainda é controverso e motivo de debate. A indicação tradicional de abordagem cirúrgica é a insuficiência cardíaca sintomática, e a realização precoce quando da identificação dos sintomas poderia prevenir remodelamento cardíaco adicional e preservar ou recuperar a função miocárdica...(AU)


Subject(s)
Humans , Atrial Fibrillation , Tricuspid Valve Insufficiency
4.
Eur J Case Rep Intern Med ; 4(9): 000692, 2017.
Article in English | MEDLINE | ID: mdl-30755967

ABSTRACT

Interrupted aortic arch (IAA) is a rare congenital abnormality with only a few cases reported in adults. It is defined as complete loss of continuity between the ascending and descending portions of the aorta, and is usually associated with other cardiac defects. The diagnosis in adults should be suspected in the presence of refractory hypertension, a careful physical examination being crucial to early diagnosis. Magnetic resonance angiography (MRA) techniques can accurately characterize cardiovascular anatomy, and also provide information regarding heart chamber and valve function. LEARNING POINTS: Although rare, interrupted aortic arch (IAA) must be considered in the differential diagnosis of adults with refractory hypertension. A careful physical examination, with evaluation of femoral pulses and blood pressure in the four limbs, is essential for the diagnosis and for ensuring that the correct diagnosis is made promptly.This case highlights the value of magnetic resonance angiography (MRA) in radiation-free non-invasive evaluation of adults with congenital aortic abnormalities, as it may provide clinically important haemodynamic information.Only a few cases have been reported in adults. We present an unusual case in which the diagnosis was not made until adulthood.

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