Retropectoral Fat Graft Survival in Mammoplasty: Evaluation by Magnetic Resonance Imaging.

BACKGROUND: Fat grafting is used in combination with mammoplasty to improve filling of the upper pole of the breasts. Its effectiveness remains in question due to unpredictable results. Difficulty in isolating the grafted fat and differentiating it from host tissues may hinder assessment of graft integration. The plane between the pectoral muscles is free of fat and has already been described with respect to placement of breast implants and fat grafting in breast surgeries. This study sought to evaluate via magnetic resonance imaging (MRI) the integration and retention of retropectoral fat grafts in mammoplasty. METHODS: Thirty patients with breast flaccidity who desired to undergo mammoplasty were selected. Fat collected from the abdomen was separated by sedimentation and transferred to the retropectoral region after undermining of the breast and resection of excess tissue. The patients underwent MRI preoperatively and at three and six months after surgery. Fat volumes were calculated by multiplying the values for the major vertical, horizontal, and anteroposterior axes by the constant 0.523. RESULTS: Twenty-five patients completed the study. The mean volume grafted was 116.4 ± 22.5 ml per breast. Six months after surgery, the mean fat graft volume in the retropectoral plane was 48.1 ± 25.71 ml, and the integration rate was 40.82% (range, 32.2-49.4%). The rate of complications related to fat grafting was 8%. CONCLUSIONS: In mammoplasty, retropectoral fat grafting showed good integration rates and is a safe and predictable approach that can contribute to improving the outcomes of aesthetic and reconstructive breast surgeries. LEVEL OF EVIDENCE IV, COHORT ANALYTIC STUDY: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Evaluation of Retropectoral Fat Grafting in Breast Reduction by Magnetic Resonance Imaging: A Pilot Study.

BACKGROUND: One of the challenges in breast reduction is to maintain breast projection with 45% of its volume in the upper pole and 55% in the lower pole. Although widely used in breast surgeries, the behavior of fat grafts is still not completely understood. OBJECTIVES: To evaluate by magnetic resonance imaging (MRI) the survival of fat transferred to the retropectoral plane in patients undergoing breast reduction, in the search for an oncologically safe procedure with high predictability and reproducibility. METHODS: This pilot study was conducted with 7 patients who underwent breast reduction combined with fat grafting in the submuscular plane. Aspirated fat was processed by sedimentation. MRI of the breasts was performed preoperatively and at 1 and 6 months postoperatively. Fat survival was calculated as the difference between the volumes of fat measured preoperatively and postoperatively by MRI divided by the volume of grafted fat. RESULTS: Fourteen breasts were operated on and received on average 119.6 mL of autologous fat in the submuscular plane. Fat survival rate was 43.9% at 1 month after surgery, decreasing to 23.4% in the late postoperative period. The mean anteroposterior projection of the grafted tissue was 1.51 cm at 1 month postoperatively, decreasing to 1.07 cm in the late postoperative period. CONCLUSIONS: Retropectoral fat grafting may contribute to maintaining the fullness of the upper pole of the breasts. This is an innovative experimental model for future studies on fat harvesting, preparation, and grafting techniques, allowing the evaluation of fat graft survival.