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1.
Arch Cardiovasc Dis ; 101(4): 235-41, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18654098

ABSTRACT

PURPOSE: Evaluate heart failure management in a Military Hospital in 2005. METHODS: Retrospective audit of 46 case records of patients hospitalised with heart failure within the framework of an accreditation procedure. RESULTS: The left ventricular ejection fraction was evaluated in 85% of cases during the reference hospital stay. Systolic heart failure was detected in 63% of cases. At least one NT-proBNP assay was performed for each patient. A global assessment was systematically performed, except for the mini mental state examination in patients aged over 75 years who represented 80% of patients. Initial therapeutic education was provided for 50% of systolic heart failure patients. Prescription rates in systolic heart failure were 76% for angiotensin-converting enzyme inhibitors, 7% for angiotensin receptor antagonists; 84% for at least one medicinal product in the above 2 classes; 68% for beta-blockers and 32% for spironolactone. A hospital discharge report was available for 93% of the patients. Elective re-admissions to hospital for uptitration of treatment concerned 10% of systolic heart failure patients. Emergency hospital re-admissions after a cardiovascular event (usually decompensation), concerned 35% of patients, after an average duration of one year of follow-up. These latter re-admissions, often repeated, led to 4% of additional hospital deaths. The initial hospital mortality rate was 13%. CONCLUSION: Therapeutic patient education is under development. Medication may still be optimised, both qualitatively and quantitatively. Surveillance is planned with a yearly audit.


Subject(s)
Heart Failure/drug therapy , Medical Audit , Adrenergic beta-Antagonists/therapeutic use , Angiotensin II Type 1 Receptor Blockers/therapeutic use , Diet , Diuretics/therapeutic use , Drug Utilization , Follow-Up Studies , France/epidemiology , Heart Failure/diagnosis , Heart Failure/etiology , Hospital Mortality , Hospitalization , Hospitals, Military , Humans , Life Style , Natriuretic Peptide, Brain/blood , Patient Education as Topic , Patient Readmission/statistics & numerical data , Peptide Fragments/blood , Quality Assurance, Health Care , Retrospective Studies , Spironolactone/therapeutic use
2.
Diabetes Metab ; 34(1): 26-32, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18249023

ABSTRACT

UNLABELLED: All diabetes specialists are aware of the frequency and severity of coronary disease in diabetics. Non-invasive diagnostic tests perform well, but they could be better. AIM: To assess the role of computed tomographic coronary angiography in diabetics. New cardiac imaging techniques such as CT coronary angiography are promising tools for the selection of patients for conventional X-ray coronary angiography, which remains the key for diagnosis and angioplasty. The limitations of CT coronary angiography, even using the most advanced machines with a 64-slice capacity, are its resolution, the need for an iodine contrast agent and the cumulative radiation from repeated examinations. CONCLUSION: CT coronary angiography appears to have great potential for patients at risk where non-invasive tests cannot absolutely exclude coronary disease and for the follow-up of coronary bypass surgery.


Subject(s)
Coronary Angiography/methods , Coronary Disease/diagnostic imaging , Diabetic Angiopathies/diagnostic imaging , Tomography, X-Ray Computed/methods , Calcium/metabolism , Humans
3.
Rev Med Interne ; 28(12): 866-70, 2007 Dec.
Article in French | MEDLINE | ID: mdl-17611002

ABSTRACT

INTRODUCTION: The role of catecholamines in the cardiac expression of pheochromocytoma is well-known. The physiopathology of the syndrome of Tako-tsubo remains more unclear. EXEGESIS: We describe 2 clinical cases of acute coronary syndrome with left ventricular dysfunction and no coronary artery stenosis. The first, a syndrome of Tako-tsubo, also known as transient left ventricular apical ballooning syndrome, is characterized by transient wall-motion in the absence of obstructive epicardial coronary disease. The second is a pheochromocytoma with myocardial suffering during hypertension crisis. Through the similarities of these 2 observations, we discuss the physiopathological assumptions to explain the syndrome of Tako-tsubo by underlining the essential place of the catecholamine hypersecretion. CONCLUSION: Syndrome of Tako-tsubo and pheochromocytoma are 2 distinct clinical entities. The link between these 2 affections is probably the pathogenic role in cardiac toxicity with the catecholamines.


Subject(s)
Acute Coronary Syndrome/chemically induced , Catecholamines/toxicity , Ventricular Dysfunction, Left/chemically induced , Aged , Cardiomyopathies/chemically induced , Catecholamines/metabolism , Female , Fires , Humans , Middle Aged , Syndrome
5.
Arch Mal Coeur Vaiss ; 95(6): 601-5, 2002 Jun.
Article in French | MEDLINE | ID: mdl-12138820

ABSTRACT

In the light of a new case revealed by a stroke, the authors confirm the importance of transesophagal echocardiography (TEE), and show that multislide computered tomography can be used as a new efficient tool for the diagnosis of cardiac papillary fibroelastoma (CPF). These benign tumours of endocardium are rare and case reports have been published sporadically. Stroke is an usual clinical complication and the most frequent symptom associated with CPF. Transesophageal echocardiography is the reference for diagnosis of CPF when transthoracic echocardiography is normal. When TEE is contraindicated or technically impossible, multislide computered tomography appears as an interesting alternate solution for diagnosis because of its fast acquisition and high spatial resolution. Symptomatology may be connected to either tumoral embolisation or cruoric emboli. Surgery is required for any symptomatic tumour.


Subject(s)
Echocardiography , Fibroma/diagnostic imaging , Heart Neoplasms/diagnostic imaging , Stroke/etiology , Tomography, X-Ray Computed , Aged , Diagnosis, Differential , Esophagus/diagnostic imaging , Humans , Male
6.
Arch Mal Coeur Vaiss ; 94(6): 600-4, 2001 Jun.
Article in French | MEDLINE | ID: mdl-11480158

ABSTRACT

Cocaine abuse should be considered in everyday cardiological practice for three reasons. The first one is epidemiological as there is an unprecedented increase in cocaine abuse in France and it may result in serious complications, mainly cardiovascular. The second reason concerns modality of consumption: it is usually associated with other toxic substances (including tobacco) and poly-intoxication is a more serious problem and the diagnostic difficulties are greater. Finally, chest pain is the first symptom of myocardial infarction in about 6% of cases. In cardiological practice, young adults with this symptom should be suspected of cocaine abuse and the diagnosis should be eventually confirmed by toxicological analysis.


Subject(s)
Cocaine-Related Disorders/complications , Cocaine/adverse effects , Death, Sudden, Cardiac/etiology , Dopamine Uptake Inhibitors/adverse effects , Myocardial Infarction/chemically induced , Adolescent , Adult , Chest Pain/chemically induced , Chest Pain/etiology , Humans , Hypertrophy, Left Ventricular/chemically induced
7.
Ann Cardiol Angeiol (Paris) ; 49(8): 473-9, 2000 Dec.
Article in French | MEDLINE | ID: mdl-12555435

ABSTRACT

Cardiovascular disease is the main cause of mortality in chronic alcoholics. There is a clear association between excessive alcohol consumption and the risk of sudden cardiac death. The pro-arrhythmogenic effect of ethanol could be responsible for some of these cases of arrhythmia and sudden death in subjects with an alcoholic cardiomyopathy and also in those with an apparently normal heart. In any case of supraventricular or ventricular arrhythmia in a chronic alcoholic or in an occasional heavy drinker, the potential role of alcohol consumption in the initiation of these disorders should be considered. In all cases, patient management consists of detoxification and abstaining from alcohol consumption, but the withdrawal period is particularly critical as regards the risk of ventricular arrhythmias.


Subject(s)
Alcohol Drinking/adverse effects , Alcoholism/complications , Arrhythmias, Cardiac/etiology , Arrhythmias, Cardiac/diagnosis , Arrhythmias, Cardiac/epidemiology , Arrhythmias, Cardiac/physiopathology , Arrhythmias, Cardiac/therapy , Humans
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