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Chem Commun (Camb)
; 51(60): 12134-7, 2015 Aug 04.
Article
in English
| MEDLINE
| ID: mdl-26126593
ABSTRACT
Principal component analysis was applied to a biomaterial library of poly(beta-amino ester)s, useful for non-viral gene delivery, to elucidate chemical parameters that drive biological function. Correlative relationships and principal components were analyzed between 24 physico-chemical polymer properties and 3 cell-based functional variables in human glioblastoma cells (transfection, uptake, and viability).