[Detection rate of carotid artery plaque in Uygur, Kazakh and Han populations of Xinjiang].

OBJECTIVE: To investigate the detection rate of carotid artery plaque in Han, Uygur and Kazakh adult populations of Xinjiang. METHODS: During the period of October 2007 to March 2010, the present study was performed in 13896 Han, Uygur and Kazakh adults of Xinjiang aged 35 years old and over by a four-stage random sampling method. All subjects were investigated by a standardized questionnaire, physical, biochemical examination and ultrasonography of carotid arteries. Risk factors were analyzed by a logistic regression model. RESULTS: The prevalence of carotid artery plaque was 10.2%. After standardization, the detection rate of Chinese Han, Uygur and Kazakh populations was 2.46%, 2.31% and 1.84% respectively. By the analysis of multivariate logistic regression, age (OR 1.032, 95%CI 1.026-1.037), smoking (OR 1.358, 95%CI 1.164-1.585), total cholesterol (OR 1.075, 95%CI 1.018-1.135), blood glucose (OR 1.050, 95%CI 1.020-1.081) and systolic blood pressure (OR 1.011, 95%CI 1.008-1.014) were independent risk factors in the occurrence of carotid artery plaque. Females (OR 0.653, 95%CI 0.545-0.738) and high-density lipoprotein (OR 0.864, 95%CI 0.751-0.994) were the protective factors in the occurrence of carotid artery plaque. CONCLUSION: The detection of carotid artery plaque in Xinjiang increases substantially with age and difference exists between nationalities. The associated risk factors of the formation of carotid artery plaque include gender, age, smoking, high-density lipoprotein, total cholesterol, blood glucose and systolic blood pressure. The effect of these factors is different between genders.

Epidemiological survey of carotid artery intima-media thickness in Han, Uygur and Hazakh population of Xinjiang Uygur autonomous region / 中华心血管病杂志

<p><b>OBJECTIVE</b>To investigate carotid artery intima-media thickness (IMT) and the correlated risk factors in Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region.</p><p><b>METHOD</b>Cross-sectional and cluster sampling random selected method was carried out for residents over 35 years old in Han, Uygur, Hazakh population of Xinjiang to investigate IMT and correlated risk factors.</p><p><b>RESULTS</b>IMT of Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region was (0.0761 ± 0.0283) cm, (0.0663 ± 0.0262) cm, and (0.0781 ± 0.0274) cm, respectively. There were significantly difference between various nationality (all P < 0.05). IMT was thicker in male Han people than in female Han people [(0.0807 ± 0.0288) cm vs. (0.0717 ± 0.0270) cm, P < 0.01] and in male Uygur than in female Uygur residents [(0.0706 ± 0.0270) cm vs. (0.0633 ± 0.0252) cm, P < 0.01] and in male Hazakh and female Hazakh residents [(0.0794 ± 0.0280) cm vs. (0.0768 ± 0.0268) cm, P < 0.01]. Linear correlation analysis showed that age (r = 0.176, P < 0.05), systolic blood pressure (r = 0.168, P < 0.05), diastolic blood pressure (r = 0.167, P < 0.05), fasting blood glucose (r = 0.053, P < 0.05), total cholesterol (r = 0.097, P < 0.05) and ankle brachial index (r = 0.067, P < 0.05) were significantly correlated with IMT.</p><p><b>CONCLUSIONS</b>Our results showed that IMT was thicker in Hazakh residents than in Han and Uygur residents. IMT was closely related to known cardiovascular risk factors including age, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol and ankle brachial index level.</p>

[Association of ankle-brachial index and pulse wave velocity with stroke in Han, Uighur, and Kazakh population of Xinjiang].

OBJECTIVE: To investigate the relationship between stroke and ankle-brachial index (ABI), pulse wave velocity (PWV) in Han, Uighur, and Kazakh populations of Xinjiang. METHODS: Data was from the investigation of cardiovascular risk survey (CRS) program among different nationalities in Xinjiang from October 2007 to March 2010. A total of 14 618 samples aged over 35 with complete data dimension were surveyed. RESULTS: (1) There were 633 patients with stroke, including 258 Hans (4.48%), 247 Uighurs (5.18%), and 128 Kazakhs (3.13%). The incidence of stroke was significant different in the three ethnic groups (P < 0.001). (2) Compared to the Han population, the incidence of stroke was higher (OR = 1.304) in Uighur but lower (OR = 0.794) in Kazakh. (3) PWV was significant different between stroke and non-stroke patients. After adjustment for age, body mass index, systolic blood pressure, triglyceride, total cholesterol and other risk factors, the difference remained significant, indicating that PWV (OR = 1.001, P < 0.001) might associate with the occurrence of stroke. CONCLUSION: The results of this study showed that the incidence of stroke was significantly different in the three ethnic groups. PWV might associate with the occurrence of stroke.

[Incidence and distributing feature of chronic heart failure in adult population of Xinjiang].

OBJECTIVE: To investigate the prevalence and distributing feature of chronic heart failure (CHF) in adult population of Xinjiang. METHODS: Four-stage random sampling method was used to analyze the prevalence and distributing feature of self-reported congestive heart failure among different nationalities in adult (35 years and over) population of Xinjiang. Sampling was collected from 6 localities (Urumqi, Kelamayi, Fukang, Turfan Basin, Hetian, Yili Hazakh). RESULTS: A total of 8459 adults were surveyed. The prevalence of CHF was 1.26% in this cohort. The prevalence of CHF was 0.89%, 1.11% and 2.14%(*) in Han, Uygur and Hazakh population, respectively ((*)P < 0.05 vs. Han and Uygur). The risk of CHF was higher in the males than in the females (1.61% vs. 0.93%, u = 2.79, P < 0.05). The prevalence of CHF increased in proportion with aging and was 0.29%, 0.60%, 1.32%, 2.55% and 4.10% in 35 - 44, 45 - 54, 55 - 64, 65 - 74, 75 years and over age groups, respectively. Common complications of CHF were hypertension (63.55%), coronary heart disease (42.99%), diabetes (18.69%), valvular heart disease (5.61%) and atrial fibrillation (4.67%). CONCLUSION: The prevalence of CHF in Xinjiang was higher than the average level in China (0.9%) and was the highest in the Hazakh population.