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1.
Clin Breast Cancer ; 24(1): 65-71, 2024 01.
Article in English | MEDLINE | ID: mdl-37852897

ABSTRACT

INTRODUCTION: implants are the most popular means of restoring the breast mound after mastectomy; the most feared complication is implant infection accounting for 4.8% to 35.4% of cases. Various antibiotic regimens or other surgical revisions to treat implant infections have been reported, but their failure rates are unacceptable. Implant removal is subsequently the most common recourse for managing prosthesis infections. we report preliminary results of infected breast implant salvage using our Regina Elena Institute (REI) protocol. METHODS: Since June 2021, a prospective single-centre study has been ongoing for patients burdened by implant infection or exposure. All qualifying participants underwent our REI protocol. They receive a temporary smooth implant and 1 week of implant's pocket irrigation with antibiotic solution along with systemic antibiotic and then a new permanent prosthesis positioning. RESULTS: Ten of whom completed at least 6 months of follow-up and were eligible for this preliminary analysis. Overall, the REI protocol was applied to 13 breasts. No infections relapsed during the 6-month minimum follow-up intervals; and no early capsular contraction was evident, resulting in good cosmetic outcomes for every treated breast. DISCUSSION: The smooth-surfaced implant's sizer helps maintain tissue expansion, preventing skin retraction; and the slightly smaller diameters used (compared with originals) facilitate antibiotic wash distribution. Combining a targeted systemic antibiotic and a topical agent is the best way to optimise infection resolution. This preliminary analysis has clear limitations. A larger population is warranted to increase the level of evidence. Longer follow-up is also advisable to monitor for delayed infection recurrence.


Subject(s)
Breast Implants , Breast Neoplasms , Mammaplasty , Humans , Female , Breast Implants/adverse effects , Prospective Studies , Breast Neoplasms/surgery , Breast Neoplasms/drug therapy , Mastectomy/adverse effects , Mammaplasty/methods , Anti-Bacterial Agents/therapeutic use , Retrospective Studies
2.
J Exp Clin Cancer Res ; 34: 120, 2015 Oct 14.
Article in English | MEDLINE | ID: mdl-26467095

ABSTRACT

INTRODUCTION: In women with macromastia, a type IV skin sparing mastectomy is often required to achieve an aesthetically pleasing reconstruction. The introduction of "skin-reducing mastectomy", which inserts a permanent prosthetic device into a large pouch made by the pectoralis major muscle and an inferior pedicle dermal flap, allows the surgeon to achieve a safe oncologic result plus a cosmetically satisfying reconstruction. OBJECTIVE: We report here our experience with the skin-reducing mastectomy with the aim of emphasizing the problems associated with the technique. MATERIALS AND METHOD: A study was conduced from April 2009 to November 2012, 74 patients with breast cancer were selected then received a skin-reducing mastectomy. The enrolled women satisfied the criteria of Nava. Statistical analysis was conduced to estimate the significance of the outcome results and complication rate. RESULT: A total of 88 SRMs were performed and the outcomes were as follows: excellent in 34 patients, good in 21, and poor in 8. We recorded 25 % of adverse events and statistic helped us to identify patient related factors whose can increase the complications onset. CONCLUSION: Skin-reducing mastectomy is an indispensable procedure to treat cancer in large and pendulous breasts. The correct patient selection is mandatory to reduce the not negligible complication risk. Skin reducing mastectomy when is well conduced allow to obtain good results with patient satisfaction but, like other breast-conserving surgeries, in some case is not the ultimate solution, because it may require some revisions to maintain the optimum results. To day it be consider relatively safe in selected patient and the gold standard in macormastia immediate reconstruction.


Subject(s)
Breast/abnormalities , Breast/surgery , Hypertrophy/surgery , Mammaplasty/methods , Mastectomy, Segmental/methods , Organ Sparing Treatments/methods , Adult , Aged , Breast/pathology , Breast Neoplasms/surgery , Female , Humans , Middle Aged , Patient Satisfaction , Retrospective Studies , Surgical Flaps/surgery
3.
Aesthetic Plast Surg ; 35(5): 731-7, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21336945

ABSTRACT

BACKGROUND: We propose a new, simple, and reliable method of nipple reconstruction using a star flap and a free graft of a linear fragment of scar tissue. The harvested fragment is deepithelialized and fixed under the flap to give the reconstruction consistency and make it steady. METHODS: The study included 218 nipple reconstructions performed between 2002 and 2008. In an attempt to estimate their satisfaction, patients were then asked to complete a 1-year postoperative questionnaire. Patients were directed to use a numerical scale of 1-10, with 1 as the worst outcome and 10 as the best possible outcome. RESULTS: The average projection of the nipple in the immediate postoperative period was 7.08 ± 0.5 mm (mean ± standard deviation). After 1 year, the average projection of the reconstructed nipple was 6.08 ± 0.5 mm. The average diameter of the reconstructed nipple in the immediate postoperative period was 14.9 ± 3 mm. After 1 year, the average diameter of the reconstructed nipple was 14.2 ± 4 mm. The average patient satisfaction with nipple projection was 7.28, sensation of the nipple, 4.11; color of the nipple, 6.36; position of the reconstructed nipple, 7.34; and symmetry compared with the opposite nipple-areola complex, 7.97. Overall patient satisfaction was 6.61. CONCLUSION: We maintain that the technique presented here is safe, easy to perform, and reproducible and improves the long-term projection of the reconstructed nipple.


Subject(s)
Cicatrix/surgery , Mammaplasty/methods , Nipples/surgery , Patient Satisfaction/statistics & numerical data , Skin Transplantation/methods , Adult , Breast Neoplasms/surgery , Cohort Studies , Esthetics , Female , Humans , Italy , Mastectomy/adverse effects , Mastectomy/methods , Middle Aged , Retrospective Studies , Risk Assessment , Surgical Flaps/blood supply , Tissue and Organ Harvesting/methods , Wound Healing/physiology
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