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1.
BMC Med Inform Decis Mak ; 24(1): 142, 2024 May 27.
Article in English | MEDLINE | ID: mdl-38802836

ABSTRACT

Lung cancer remains a leading cause of cancer-related mortality globally, with prognosis significantly dependent on early-stage detection. Traditional diagnostic methods, though effective, often face challenges regarding accuracy, early detection, and scalability, being invasive, time-consuming, and prone to ambiguous interpretations. This study proposes an advanced machine learning model designed to enhance lung cancer stage classification using CT scan images, aiming to overcome these limitations by offering a faster, non-invasive, and reliable diagnostic tool. Utilizing the IQ-OTHNCCD lung cancer dataset, comprising CT scans from various stages of lung cancer and healthy individuals, we performed extensive preprocessing including resizing, normalization, and Gaussian blurring. A Convolutional Neural Network (CNN) was then trained on this preprocessed data, and class imbalance was addressed using Synthetic Minority Over-sampling Technique (SMOTE). The model's performance was evaluated through metrics such as accuracy, precision, recall, F1-score, and ROC curve analysis. The results demonstrated a classification accuracy of 99.64%, with precision, recall, and F1-score values exceeding 98% across all categories. SMOTE significantly enhanced the model's ability to classify underrepresented classes, contributing to the robustness of the diagnostic tool. These findings underscore the potential of machine learning in transforming lung cancer diagnostics, providing high accuracy in stage classification, which could facilitate early detection and tailored treatment strategies, ultimately improving patient outcomes.


Subject(s)
Lung Neoplasms , Neural Networks, Computer , Tomography, X-Ray Computed , Humans , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/classification , Machine Learning , Image Processing, Computer-Assisted/methods , Deep Learning
2.
BMC Med Imaging ; 24(1): 107, 2024 May 11.
Article in English | MEDLINE | ID: mdl-38734629

ABSTRACT

This study addresses the critical challenge of detecting brain tumors using MRI images, a pivotal task in medical diagnostics that demands high accuracy and interpretability. While deep learning has shown remarkable success in medical image analysis, there remains a substantial need for models that are not only accurate but also interpretable to healthcare professionals. The existing methodologies, predominantly deep learning-based, often act as black boxes, providing little insight into their decision-making process. This research introduces an integrated approach using ResNet50, a deep learning model, combined with Gradient-weighted Class Activation Mapping (Grad-CAM) to offer a transparent and explainable framework for brain tumor detection. We employed a dataset of MRI images, enhanced through data augmentation, to train and validate our model. The results demonstrate a significant improvement in model performance, with a testing accuracy of 98.52% and precision-recall metrics exceeding 98%, showcasing the model's effectiveness in distinguishing tumor presence. The application of Grad-CAM provides insightful visual explanations, illustrating the model's focus areas in making predictions. This fusion of high accuracy and explainability holds profound implications for medical diagnostics, offering a pathway towards more reliable and interpretable brain tumor detection tools.


Subject(s)
Brain Neoplasms , Deep Learning , Magnetic Resonance Imaging , Humans , Brain Neoplasms/diagnostic imaging , Magnetic Resonance Imaging/methods , Image Interpretation, Computer-Assisted/methods
3.
BMC Med Imaging ; 24(1): 82, 2024 Apr 08.
Article in English | MEDLINE | ID: mdl-38589813

ABSTRACT

Breast Cancer is a significant global health challenge, particularly affecting women with higher mortality compared with other cancer types. Timely detection of such cancer types is crucial, and recent research, employing deep learning techniques, shows promise in earlier detection. The research focuses on the early detection of such tumors using mammogram images with deep-learning models. The paper utilized four public databases where a similar amount of 986 mammograms each for three classes (normal, benign, malignant) are taken for evaluation. Herein, three deep CNN models such as VGG-11, Inception v3, and ResNet50 are employed as base classifiers. The research adopts an ensemble method where the proposed approach makes use of the modified Gompertz function for building a fuzzy ranking of the base classification models and their decision scores are integrated in an adaptive manner for constructing the final prediction of results. The classification results of the proposed fuzzy ensemble approach outperform transfer learning models and other ensemble approaches such as weighted average and Sugeno integral techniques. The proposed ResNet50 ensemble network using the modified Gompertz function-based fuzzy ranking approach provides a superior classification accuracy of 98.986%.


Subject(s)
Breast Neoplasms , Female , Humans , Breast Neoplasms/diagnostic imaging , Early Detection of Cancer , Mammography , Databases, Factual , Machine Learning
4.
BMC Med Inform Decis Mak ; 24(1): 113, 2024 Apr 30.
Article in English | MEDLINE | ID: mdl-38689289

ABSTRACT

Brain tumors pose a significant medical challenge necessitating precise detection and diagnosis, especially in Magnetic resonance imaging(MRI). Current methodologies reliant on traditional image processing and conventional machine learning encounter hurdles in accurately discerning tumor regions within intricate MRI scans, often susceptible to noise and varying image quality. The advent of artificial intelligence (AI) has revolutionized various aspects of healthcare, providing innovative solutions for diagnostics and treatment strategies. This paper introduces a novel AI-driven methodology for brain tumor detection from MRI images, leveraging the EfficientNetB2 deep learning architecture. Our approach incorporates advanced image preprocessing techniques, including image cropping, equalization, and the application of homomorphic filters, to enhance the quality of MRI data for more accurate tumor detection. The proposed model exhibits substantial performance enhancement by demonstrating validation accuracies of 99.83%, 99.75%, and 99.2% on BD-BrainTumor, Brain-tumor-detection, and Brain-MRI-images-for-brain-tumor-detection datasets respectively, this research holds promise for refined clinical diagnostics and patient care, fostering more accurate and reliable brain tumor identification from MRI images. All data is available on Github: https://github.com/muskan258/Brain-Tumor-Detection-from-MRI-Images-Utilizing-EfficientNetB2 ).


Subject(s)
Brain Neoplasms , Deep Learning , Magnetic Resonance Imaging , Humans , Brain Neoplasms/diagnostic imaging , Magnetic Resonance Imaging/methods , Image Interpretation, Computer-Assisted/methods , Artificial Intelligence
5.
Sci Rep ; 14(1): 7818, 2024 Apr 03.
Article in English | MEDLINE | ID: mdl-38570527

ABSTRACT

In wireless networking, the security of flying ad hoc networks (FANETs) is a major issue, and the use of drones is growing every day. A distributed network is created by a drone network in which nodes can enter and exit the network at any time. Because malicious nodes generate bogus identifiers, FANET is unstable. In this research study, we proposed a threat detection method for detecting malicious nodes in the network. The proposed method is found to be most effective compared to other methods. Malicious nodes fill the network with false information, thereby reducing network performance. The secure ad hoc on-demand distance vector (AODV) that has been suggested algorithm is used for detecting and isolating a malicious node in FANET. In addition, because temporary flying nodes are vulnerable to attacks, trust models based on direct or indirect reliability similar to trusted neighbors have been incorporated to overcome the vulnerability of malicious/selfish harassment. A node belonging to the malicious node class is disconnected from the network and is not used to forward or forward another message. The FANET security performance is measured by throughput, packet loss and routing overhead with the conventional algorithms of AODV (TAODV) and reliable AODV secure AODV power consumption decreased by 16.5%, efficiency increased by 7.4%, and packet delivery rate decreased by 9.1% when compared to the second ranking method. Reduced packet losses and routing expenses by 9.4%. In general, the results demonstrate that, in terms of energy consumption, throughput, delivered packet rate, the number of lost packets, and routing overhead, the proposed secure AODV algorithm performs better than the most recent, cutting-edge algorithms.

6.
BMC Med Imaging ; 24(1): 100, 2024 Apr 29.
Article in English | MEDLINE | ID: mdl-38684964

ABSTRACT

PURPOSE: To detect the Marchiafava Bignami Disease (MBD) using a distinct deep learning technique. BACKGROUND: Advanced deep learning methods are becoming more crucial in contemporary medical diagnostics, particularly for detecting intricate and uncommon neurological illnesses such as MBD. This rare neurodegenerative disorder, sometimes associated with persistent alcoholism, is characterized by the loss of myelin or tissue death in the corpus callosum. It poses significant diagnostic difficulties owing to its infrequency and the subtle signs it exhibits in its first stages, both clinically and on radiological scans. METHODS: The novel method of Variational Autoencoders (VAEs) in conjunction with attention mechanisms is used to identify MBD peculiar diseases accurately. VAEs are well-known for their proficiency in unsupervised learning and anomaly detection. They excel at analyzing extensive brain imaging datasets to uncover subtle patterns and abnormalities that traditional diagnostic approaches may overlook, especially those related to specific diseases. The use of attention mechanisms enhances this technique, enabling the model to concentrate on the most crucial elements of the imaging data, similar to the discerning observation of a skilled radiologist. Thus, we utilized the VAE with attention mechanisms in this study to detect MBD. Such a combination enables the prompt identification of MBD and assists in formulating more customized and efficient treatment strategies. RESULTS: A significant breakthrough in this field is the creation of a VAE equipped with attention mechanisms, which has shown outstanding performance by achieving accuracy rates of over 90% in accurately differentiating MBD from other neurodegenerative disorders. CONCLUSION: This model, which underwent training using a diverse range of MRI images, has shown a notable level of sensitivity and specificity, significantly minimizing the frequency of false positive results and strengthening the confidence and dependability of these sophisticated automated diagnostic tools.


Subject(s)
Deep Learning , Magnetic Resonance Imaging , Marchiafava-Bignami Disease , Humans , Marchiafava-Bignami Disease/diagnostic imaging , Magnetic Resonance Imaging/methods , Male , Female , Middle Aged , Adult , Image Interpretation, Computer-Assisted/methods , Sensitivity and Specificity
7.
Sci Rep ; 14(1): 3741, 2024 02 14.
Article in English | MEDLINE | ID: mdl-38355896

ABSTRACT

Inadequate conservation of medicinal plants can affect their productivity. Traditional assessments and strategies are often time-consuming and linked with errors. Utilizing herbs has been an integral part of the traditional system of medicine for centuries. However, its sustainability and conservation are critical due to climate change, over-harvesting and habitat loss. The study reveals how machine learning algorithms, geographic information systems (GIS) being a powerful tool for mapping and spatial analysis, and soil information can contribute to a swift decision-making approach for actual forethought and intensify the productivity of vulnerable curative plants of specific regions to promote drug discovery. The data analysis based on machine learning and data mining techniques over the soil, medicinal plants and GIS information can predict quick and effective results on a map to nurture the growth of the herbs. The work incorporates the construction of a novel dataset by using the quantum geographic information system tool and recommends the vulnerable herbs by implementing different supervised algorithms such as extra tree classifier (EXTC), random forest, bagging classifier, extreme gradient boosting and k nearest neighbor. Two unique approaches suggested for the user by using EXTC, firstly, for a given subregion type, its suitable soil classes and secondly, for soil type from the user, its respective subregion labels are revealed, finally, potential medicinal herbs and their conservation status are visualised using the choropleth map for classified soil/subregion. The research concludes on EXTC as it showcases outstanding performance for both soil and subregion classifications compared to other models, with an accuracy rate of 99.01% and 98.76%, respectively. The approach focuses on serving as a comprehensive and swift reference for the general public, bioscience researchers, and conservationists interested in conserving medicinal herbs based on soil availability or specific regions through maps.


Subject(s)
Plants, Medicinal , Soil , Machine Learning , Ecosystem , Algorithms
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