Subject(s)
Bone Neoplasms/radiotherapy , Lymphoma, Non-Hodgkin/radiotherapy , Adolescent , Adult , Biopsy , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/pathology , Female , Humans , Humerus/pathology , Lymphoma, Non-Hodgkin/diagnostic imaging , Lymphoma, Non-Hodgkin/pathology , Male , Radiography , Radiotherapy DosageABSTRACT
The authors studied clinically, roentgenologically and morphologically 8 patients with radiation osteogenic bone sarcomas which the patients developed 9 to 24 years (15 years, on the average) after distant gamma therapy at total local doses from 35 to 111 Gy (average 63 Gy) for primary skeletogenic and non-skeletogenic tumors when the bone was in the zone of irradiation. Radiation osteogenic sarcomas developed when the women or patients at early age were irradiated. Osteosclerotic (3), osteoblastic (2), osteoid (1), chondroblastic (2) forms of osteogenic sarcoma were identified. Necrotic and regeneratory bone changes preceding tumour growth may be found that alter the roentgenomorphological correlations.
Subject(s)
Bone Neoplasms/pathology , Neoplasms, Radiation-Induced/pathology , Osteosarcoma/pathology , Adolescent , Adult , Child , Child, Preschool , Gamma Rays , Humans , Middle AgedSubject(s)
Bone Neoplasms/secondary , Head and Neck Neoplasms/pathology , Paraganglioma, Extra-Adrenal/secondary , Adult , Female , Humans , MaleABSTRACT
In 6 patients with sarcomas of the bones of the crus at different periods following radiotherapy the authors have revealed pathologic reconstruction of the structure of the tibia. A roentgenologic picture of the changes in the course of the dynamic observation of the patients and their treatment is presented. It has been demonstrated that the conservative treatment effective.
Subject(s)
Osteoradionecrosis , Radiation Injuries , Radiotherapy/adverse effects , Tibia/radiation effects , Bone Neoplasms/radiotherapy , Child , Female , Fibula , Humans , Male , Osteoradionecrosis/therapy , Osteosarcoma/radiotherapy , Radiation Injuries/therapy , Radiography , Radiotherapy Dosage , Sarcoma, Ewing/radiotherapy , Tibia/diagnostic imagingSubject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Femur Head Necrosis/etiology , Hodgkin Disease/therapy , Adult , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Combined Modality Therapy , Female , Hodgkin Disease/drug therapy , Hodgkin Disease/radiotherapy , Humans , Male , Radiotherapy/adverse effectsABSTRACT
The results of examination of 12 patients with vertebral radiation injuries were analyzed. The authors considered clinical and x-ray signs of radiation osteoporosis (5), radiation osteonecrosis (7 patients), and complications in the form of pathological fractures of vertebral bodies. Vertebral radiation injuries were most frequently detected 6-12 yrs. after the discontinuation of radiotherapy.
Subject(s)
Cervical Vertebrae/radiation effects , Lumbar Vertebrae/radiation effects , Radiotherapy/adverse effects , Thoracic Vertebrae/radiation effects , Adult , Cervical Vertebrae/diagnostic imaging , Female , Fractures, Bone/diagnostic imaging , Fractures, Bone/etiology , Humans , Lumbar Vertebrae/diagnostic imaging , Male , Middle Aged , Neoplasms/radiotherapy , Osteoradionecrosis/diagnostic imaging , Osteoradionecrosis/etiology , Radiography , Spinal Diseases/diagnostic imaging , Spinal Diseases/etiology , Spinal Injuries/diagnostic imaging , Spinal Injuries/etiology , Thoracic Vertebrae/diagnostic imagingSubject(s)
Breast Neoplasms/radiotherapy , Osteoporosis/etiology , Osteoradionecrosis/etiology , Radiation Injuries/complications , Radiation Injuries/etiology , Radioisotope Teletherapy/adverse effects , Adult , Aged , Clavicle/injuries , Clavicle/radiation effects , Female , Humans , Humerus/injuries , Humerus/radiation effects , Male , Middle AgedABSTRACT
The data on 53 cases of bone injuries caused by radiation treatment for cancer of the uterus were analysed. The clinico-roentgenological signs of osteoradionecrosis (33), pathological fracture and dislocation (13), osteomyelitis (5) and radiation-induced sarcoma of bone (2) were considered. Lesions were found to occur most frequently in the upper flaring portion of the ilium and bones of the hip joints. Regular X-ray examinations of the pelvic bones are necessary for early detection of radiation injuries as well as conservative treatment to prevent such grave complications as pathologic fracture and osteomyelitis.
Subject(s)
Bone Diseases/etiology , Bone Neoplasms/etiology , Neoplasms, Radiation-Induced/etiology , Radiation Injuries/etiology , Radiotherapy/adverse effects , Sarcoma/etiology , Uterine Neoplasms/radiotherapy , Adult , Bone Diseases/diagnostic imaging , Female , Fractures, Spontaneous/etiology , Humans , Joint Dislocations/etiology , Middle Aged , Osteomyelitis/diagnostic imaging , Osteomyelitis/etiology , Osteonecrosis/diagnostic imaging , Osteonecrosis/etiology , Radiography , Radiotherapy DosageSubject(s)
Alcoholic Intoxication/complications , Foot Injuries , Frostbite/complications , Foot/diagnostic imaging , Foot Diseases/diagnostic imaging , Foot Diseases/etiology , Frostbite/diagnostic imaging , Humans , Male , Middle Aged , Radiography , Radionuclide Imaging , Skin Ulcer/diagnostic imaging , Skin Ulcer/etiologyABSTRACT
Secondary tumors developed in the zone of exposure fields in 6 patients treated with radiation for different malignancies. Tumors appeared, on the average, 12 years after radiotherapy.
