1.
Boll Chim Farm
; 140(6): 428-32, 2001.
Article
in English
| MEDLINE
| ID: mdl-11822233
ABSTRACT
A Series of 4-(1-Aryl-5-oxo-2-phenyl-2-imidazolin-4-yl) metheno-5-chloro-3-methyl-1-phenyl-3-pyrazole) were synthesised and tested for their antibacterial, antiinflammatory and analagesic activities. Some of the compounds showed significant antiinflammatory properties.
Subject(s)
Analgesics, Non-Narcotic/chemical synthesis , Analgesics, Non-Narcotic/pharmacology , Anti-Bacterial Agents/chemical synthesis , Anti-Bacterial Agents/pharmacology , Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Imidazoles/chemical synthesis , Imidazoles/pharmacology , Animals , Bacteria/drug effects , Mice , Microbial Sensitivity Tests , Pain Measurement/drug effects
2.
Boll Chim Farm
; 135(11): 638-42, 1996 Dec.
Article
in English
| MEDLINE
| ID: mdl-9066173
ABSTRACT
A series of 3-(substituted anilinomethyl)-4-(5-substituted-2- furfurylidene)amino-1,2,4-triazole-5-thiones were synthesized as potential biologically active agents. They were converted to Mannich bases, by treating with suitable amine in the presence of formaldehyde in alcohol medium. The newly synthesized compounds were screened for their antibacterial and antifungal activities.
