ABSTRACT
Individuals with Down syndrome (DS) are susceptible to severe periodontal disease, due to immune alterations related to functional defects of polymorphonuclear leukocytes and monocytes. The adjunctive use of locally delivered antimicrobials has been proven to be beneficial, especially in areas where mechanical therapy might fail. This article describes the management of a patient with DS who had aggressive periodontitis. The treatment used a local drug delivery system with tetracycline fibers as an adjunct to scaling and root planing.
Subject(s)
Aggressive Periodontitis/drug therapy , Anti-Bacterial Agents/administration & dosage , Down Syndrome/complications , Drug Delivery Systems , Tetracycline/administration & dosage , Adult , Aggressive Periodontitis/therapy , Alveolar Bone Loss/drug therapy , Alveolar Bone Loss/therapy , Collagen , Combined Modality Therapy , Dental Plaque Index , Dental Scaling/methods , Drug Carriers , Female , Follow-Up Studies , Furcation Defects/drug therapy , Furcation Defects/therapy , Humans , Periodontal Attachment Loss/drug therapy , Periodontal Attachment Loss/therapy , Periodontal Index , Periodontal Pocket/drug therapy , Periodontal Pocket/therapy , Root Planing/methods , Tooth Mobility/drug therapy , Tooth Mobility/therapyABSTRACT
Rubinstein-Taybi syndrome, or broad thumb-hallux syndrome, is a well-defined rare congenital disorder characterised by postnatal growth deficiency, craniofacial dysmorphism, broad thumbs and great toes, and mental retardation (intellectual disability). Occurrence may be either sporadic or through autosomal dominant inheritance. Reports of Rubinstein-Taybi syndrome are scarce in the literature. This case report describes the oral and dentofacial findings of Rubinstein-Taybi syndrome affecting a 13-year-old Indian female, including the uncommon presence of talon cusps and an unerupted supernumerary tooth.
