ABSTRACT
Studied was the correlation between the acid-alkaline status and the antibody production in pigs treated with the VR-2 vaccine against swine erysipelas. A progressive growth of the values of the B-system indices was established as early as the 24th hour in correlation with the higher HCO3 and CO2 values. The latter substantiated a new profile of the acid-alkaline state, which persisted up to the 10th day. The subsidiary increase in the concentration of HCO3 from the 10th to the 15th day as well as of pCO2 on the 15th day was associated with the highest percent and absolute number of B lymphocytes and 'AOK' at 10(6). This confirmed the presence of a gradual correlation between the indices of the acid-alkaline state and the B system.
Subject(s)
Acid-Base Equilibrium , Antibodies, Bacterial/analysis , Bacterial Vaccines/immunology , Erysipelothrix Infections/prevention & control , Erysipelothrix/immunology , Swine Erysipelas/prevention & control , Swine/immunology , Animals , Antibody-Producing Cells/immunology , B-Lymphocytes/immunology , Immunization/veterinary , Time FactorsABSTRACT
Studied were the changes in the total count of the white blood cells, the leukocyte formula, and the T- and B-lymphocytes of young pigs (2-3 months old) at various intervals following treatment with an E. coli enterotoxin. It was found that there set in an essential drop of the total count of the white blood cells during the first 24 hours after treatment, with a following rising trend. There were also characteristic changes in the ratio between the various types of white blood cells, with a rise of the lymphocytes and monocytes. The level of T-POK and B-POK rose after the endotoxin was injected--for the T cells it reached peak values between the 3d and 5th day, while for the B cells it was highest between the 5th and 7th day. There was a following drop with both types of cells, and by the 15th day the initial level was reached.
