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1.
Drug Des Devel Ther ; 9: 5195-201, 2015.
Article in English | MEDLINE | ID: mdl-26388687

ABSTRACT

BACKGROUND: The aim of this study was to evaluate the effects of a phosphodiesterase inhibitor pentoxifylline (PTX), electromagnetic fields (EMFs), and a mixture of both materials on bone fracture healing in a rat model. MATERIALS AND METHODS: Eighty male Wistar rats were randomly divided into four groups: Group A, femur fracture model with no treatment; Group B, femur fracture model treated with PTX 50 mg/kg/day intraperitoneal injection; Group C, femur fracture model treated with EMF 1.5±0.2 Mt/50 Hz/6 hours/day; and Group D, femur fracture model treated with PTX 50 mg/kg/day intraperitoneal injection and EMF 1.5±0.2 Mt/50 Hz/6 hours/day. RESULTS: Bone fracture healing was significantly better in Group B and Group C compared to Group A (P<0.05), but Group D did not show better bone fracture healing than Group A (P>0.05). CONCLUSION: It can be concluded that both a specific EMF and PTX had a positive effect on bone fracture healing but when used in combination, may not be beneficial.


Subject(s)
Electromagnetic Fields , Femoral Fractures/therapy , Pentoxifylline/pharmacology , Phosphodiesterase Inhibitors/pharmacology , Animals , Disease Models, Animal , Fracture Healing/physiology , Injections, Intraperitoneal , Male , Rats , Rats, Wistar
2.
Article in English | MEDLINE | ID: mdl-27252961

ABSTRACT

Hands, especially lunatum, are involved very rarely with osteoid osteoma. This report presents an osteoid osteoma of the lunatum, which was previously misdiagnosed as Kienböck's disease and had undergone surgery. Magnetic resonance imaging may lead the clinician to misdiagnose because of the excessive bone edema around the carpus. The operation should be planned according to radiography and computed tomography findings.

3.
Plast Reconstr Surg Glob Open ; 2(12): e262, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25587496

ABSTRACT

SUMMARY: Tuberculosis infections are still one of the most important public health problems among developing countries. Musculoskeletal involvement represents 10-15% of all extrapulmonary cases. Tuberculosis tenosynovitis is usually misdiagnosed as nonspecific tenosynovitis. To avoid misdiagnosis and mistreatment, it is important to be alert for mycobacterial infections. This article presents 3 patients with wrist tenosynovitis, which was caused by Mycobacterium bovis infection. The article also includes review of the literature.

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