1.
Antimicrob Agents Chemother
; 31(12): 1897-900, 1987 Dec.
Article
in English
| MEDLINE
| ID: mdl-3439798
ABSTRACT
Multilamellar vesicles containing nystatin (NYS) were compared with vesicles containing the free drug for toxicity to erythrocytes and for antifungal activity in vitro. Liposomal nystatin was as active as free NYS was against a wide variety of yeasts and fungi. The antifungal activity against Candida albicans was maintained with different liposome compositions and without sterols. Liposome encapsulation also protected the erythrocytes from the toxicity of free NYS.