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1.
J Int Med Res ; 41(5): 1716-23, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24026772

ABSTRACT

OBJECTIVE: To measure Mycoplasma pneumoniae pneumonia (MPP)-associated myocardial damage in different age groups of children with pneumonia. METHODS: Children aged 0-14 years with pneumonia and myocardial damage (serum creatine kinase isoenzyme-MB [CK-MB] concentration >25 U/l) were enrolled in the study. The children were classified as Mycoplasma pneumoniae immunoglobulin M positive (M. pneumoniae IgM+) or negative (M. pneumoniae IgM-) based on a serological test. Children were stratified into four age groups in order to analyse age-specific MPP-associated myocardial damage. RESULTS: The incidence of fever was significantly higher in children who were M. pneumoniae IgM+ compared with M. pneumoniae IgM- children. The median serum CK-MB concentration was significantly higher in children who were M. pneumoniae IgM+ compared with those who were M. pneumoniae IgM-. Children who were M. pneumoniae IgM+ in the 13-36 months and 72 months-14 years age groups had significantly higher median serum CK-MB concentrations than those who were M. pneumoniae IgM- in the same age group. CONCLUSIONS: M. pneumoniae infection was associated with greater myocardial damage in children aged 13-36 months and 72 months-14 years. This suggests age-specific immune responses to M. pneumoniae.


Subject(s)
Antibodies, Bacterial/blood , Immunoglobulin M/blood , Mycoplasma pneumoniae/pathogenicity , Myocarditis/pathology , Myocardium/pathology , Pneumonia, Mycoplasma/pathology , Adolescent , Age Factors , Child , Child, Preschool , Creatine Kinase, MB Form/blood , Female , Fever/microbiology , Fever/pathology , Humans , Infant , Infant, Newborn , Male , Mycoplasma pneumoniae/physiology , Myocarditis/blood , Myocarditis/complications , Myocarditis/microbiology , Pneumonia, Mycoplasma/blood , Pneumonia, Mycoplasma/complications , Pneumonia, Mycoplasma/microbiology , Severity of Illness Index
2.
Rev Sci Instrum ; 82(4): 046103, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21529047

ABSTRACT

A high performance pulse energy detector is developed based on photoacoustic effect. Different from the detectors reported before which also utilized photoacoustic effect, our detector can measure the energy of each pulse output from a Q-switched laser and monitor the pulse energy fluctuation in real time owing to the signal processing circuit designed. By comparing with a commercial laser energy meter, our detector is proved to be of high sensitivity and accuracy. We test the detector under illumination of different pulse energy at varied wavelengths, and the results demonstrate that the detector has a broad spectral response and a dynamical energy range. Besides, the measurements of this detector will not be affected by the background light according to the principle of photoacoustic effect.

3.
Rev Sci Instrum ; 81(10): 103106, 2010 Oct.
Article in English | MEDLINE | ID: mdl-21034074

ABSTRACT

An experimental setup is built for the measurement of monochromatic incident photon-to-electron conversion efficiency (IPCE) of solar cells. With this setup, three kinds of IPCE measuring methods as well as the convenient switching between them are achieved. The setup can also measure the response time and waveform of the short-circuit current of solar cell. Using this setup, IPCE results of dye-sensitized solar cells (DSCs) are determined and compared under different illumination conditions with each method. It is found that the IPCE values measured by AC method involving the lock-in technique are sincerely influenced by modulation frequency and bias illumination. Measurements of the response time and waveform of short-circuit current have revealed that this effect can be explained by the slow response of DSCs. To get accurate IPCE values by this method, the measurement should be carried out with a low modulation frequency and under bias illumination. The IPCE values measured by DC method under the bias light illumination will be disturbed since the short-circuit current increased with time continuously due to the temperature rise of DSC. Therefore, temperature control of DSC is considered necessary for IPCE measurement especially in DC method with bias light illumination. Additionally, high bias light intensity (>2 sun) is found to decrease the IPCE values due to the ion transport limitation of the electrolyte.

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